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However, when a cultivator reaches hemp flower oil the realm of the top true immortals, although the names are the same, the real strength is also very different, and the strength of this Yuanba is absolutely cbd health benefits chart User Guide the top existence among the top true immortals.
Oh Really Ye Fan smiled, of course he knew what the third cbd health benefits chart elder meant.
Okay, since that s the case, I m not going to give up.
This is his battle to become famous, and cbd health benefits chart this old man must bow his head.
Although this method has prevented the spread of the poisonous gas to cbd candies a certain extent, the previous outbreak of the poisonous cbd oil benefits for kids mist by the power of flames Hemp Vs Marijuana Cbd cbd health benefits chart has caused many people to Hemp Vs Marijuana Cbd cbd health benefits chart fall into a state similar to that of an illusion, and they want to restore their minds.
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No wonder can cbd oil test positive in a drug test my unworthy disciples can t compete with you Feel the power of cbd health benefits chart User Guide Ye Fan.
But Ye Fan cbd oil and tylenol interaction doesn t seem to take it seriously at all.
, you wait for the little baby, do you know the gap with the old man now Where did the previous energy go Patriarch Hong Ling walked in front of the crowd, looked down at the five masters of Tiangong Pavilion, and can i put cbd oil directly into my eye for cataract Cbd Manufacturing said with a sneer.
Princess Qingwu s request was a bit excessive for someone like Song Can You Get High Off Cbd Oil cbd health benefits chart Yushu.
What s the situation What s going cbd health benefits chart on Our attack has actually stopped The five masters of Tiangong Pavilion were stunned at the same time.
Looking cbd health benefits chart at Ye smokymountainsk8way.com cbd health benefits chart Fan who was can i put cbd oil directly into my eye for cataract Cbd Manufacturing dying, Yun Qingwu was very worried, but she understood that even if Ye Fan didn t Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract stop her, her power would smokymountainsk8way.com cbd health benefits chart not be able to fight against the Tao of Heaven at all, and that would is there a limit to home much cbd oil can i produce only add chaos to smokymountainsk8way.com cbd health benefits chart Ye Fan.
Since everything is the cbd health benefits chart best, why can t it resist Ye Fan s attack In fact, not only Song Yushu, but other people present also wanted to know the secrets of Ye Fan, but who would be stupid enough to tell their own secrets Are you kidding me If you lose, you lose.
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, we finally found it, this must be the real treasure.
If the real body wants to break the shackles and come to the Big Dipper, I am afraid it will take hundreds of years, or even thousands of years.
Master Patriarch, why do you have to be so condescending, this kid is relying on these cbd health benefits chart magical soldiers to fight back cbd circle orange gummies and wait for me Now let Hemp Vs Marijuana Cbd cbd health benefits chart s kill smokymountainsk8way.com cbd health benefits chart this kid together, and then these magical soldiers can be taken as our own, isn t this a good thing Seeing that Patriarch Hong Ling kept ingratiating himself with Ye Fan, Cui Zhonghai hurried to get revenge, and was naturally very angry.
His realm is still the second layer transcending calamity.
The rough appearance creates a repressive momentum.
We didn t expect to be does cbd gummies relax you cbd health benefits chart a super formation master, which is great.
And nature, or those natural beasts, used these weaknesses to slaughter human monks.
This cbd health benefits chart scene was cbd health benefits chart too shocking, cbd oil makes skin healthier and everyone cbd health benefits chart User Guide felt a strong oppressive force that continued to spread from the center Can You Get High Off Cbd Oil cbd health benefits chart of the battlefield.
Princess Qingwu, it s all right, you stand aside, I m going to ask this bastard this time if he has a Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract holy weapon Song Yushu looked at Ye Fan coldly.
Then, the stele flew has sproutly in canada created a website to purchase cbd oil and products high into the sky, shining continuously towards cbd oil davenport iowa the bottom.
But in fact, this is their own choice, they want to get the Fengshen bell, so it is the greed that hurts them and lets them enter this space.
This is the powerful cbd oil and iron supplement Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract fighting power of Chiyou Demon God s Blood.
Just as Xu Yuntian died and disappeared, a strange bell appeared in the space, and then, three bells appeared in front of Ye Fan.
The Qiankun Formation has very strict cultivation requirements, unless it is a hemp isolate powder true cbd efficacy immortal cultivation above the sixth level of calamity, otherwise, the cultivator may cbd health benefits chart fall into the destruction of the formation and self destruct.
It s all random talk, nothing. Ye Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract Fan said.
Oh, what an idiot It s ridiculous to want to attack with can i put cbd oil directly into my eye for cataract Cbd Manufacturing cbd health benefits chart User Guide such strength.
At this moment, the vision in the sky completely dissipated, only the endless gloom and darkness descended, and the aura of killing ran across the sky.
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During this time, he searched for the fluctuation of soul power every day.
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In the main camp of the Holy Land of Hongmeng, the elder Yunshan was sitting on the throne, with Ye Fan and Yuanba below him.
If it was really like what Chu Xiang said, then things would be troublesome.
Everyone, fish cbd health benefits chart and shrimp can live an ordinary Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract life in the sea But the real dragon, cbd health benefits chart even if it stays dormant for a long time, will one day soar for nine days This sentence made everyone fall into silence.
Swish As one of the array orders oscillated, golden light flickered.
They kept rolling and screaming in agony.
But after pushing Can You Get High Off Cbd Oil cbd health benefits chart out the palm, Ye Fan fell to the ground, dying.
Keng, Keng, Keng Waving the incomparably powerful Heavenly Dragon Breaking the City Halberd, Ye Fan activated the power of the Demon God, which was unstoppable.
Even the can teenagers take cbd gummies elders cbd health benefits chart User Guide can t Hemp Vs Marijuana Cbd cbd health benefits chart handle the fog, can anyone cbd health benefits chart Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract actually disperse it For a time, everyone was shocked.
He had to understand the Shuiyue Holy Land as thoroughly as possible, because he would use it when saving Chu Mengyao.
As the most powerful Zidian Palace in control of Lei Fa, the five masters were defeated by Lei Fa, which is cbd health benefits chart too Hemp Vs Marijuana Cbd cbd health benefits chart ironic.
They not only defeated the weak water, but also attracted the thirty seven petaled smokymountainsk8way.com cbd health benefits chart golden lotus.
He is six realms cbd health benefits chart higher than Ye Fan, but he can t easily defeat Ye Fan.
This is Ye Fan s own choice, so he has to solve it himself.
This made Ye Fan interested. He just broke through himself last night and absorbed the power of the three elders.
Flaming Palm Ice Can You Get High Off Cbd Oil cbd health benefits chart Vein Hand Shi Hun Fist The three elders shot at the same time, and their powerful might dangers of taking cbd oil and ibuprofen together directly attacked the black Yinglong.
Although the hegemony body has entered the perfect state, cbd health benefits chart Ye Fan will not stop, he wants to break through himself.
Ah Xiao Chen let out a do you need a prescription for cbd oil in south carolina cbd health benefits chart roar cbd health benefits chart like a beast.
Ye Fan has been cbd health benefits chart observing the surrounding situation, using the rhinoceros horn to secretly cbd health benefits chart search for the fluctuation does cbd oil affect liver enzymes of soul power.
What Wu Yu and the others were shocked. Ye Fan cbd health benefits chart actually said that his strength was still higher than that of the ancestors of Hong Ling.
Yes, the arrogance of the Holy Land of Hongmeng is the most powerful existence.
Hey, cbd health benefits chart dr sanjay gupta interactions with cbd hemp oil and metoprolol and or corlanor Mo Tianxing is cbd health benefits chart indeed a genius of formation, it s a pity.
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Ye Fan said. That s right. Although Chang Daoqin said so, but as an array mage at the rank cbd health benefits chart User Guide of array saint, he would not believe Ye Fan s words.
Ye Fan could completely point out Patriarch s formation before leaving shark tank cbd gummies to quit smoking safely.
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The holy cbd health benefits chart light of the golden lotus of merit is still going on.
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The more powerful the magic weapon, the more difficult it is to control.
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Now he can t fight against other emperors, because he used a forbidden move in order to defeat how long does it take for cbd oil to start working for anxiety the demon king Bo Xun.
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This kind of ordinary disciple who is just getting started can have this kind of magic weapon.
Ye Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract Fan, please clarify, so that everyone can understand your difficulties.
He really wanted to see how strong the formation of the ancestors of Hong Ling was , the patriarch has come out Cui Zhonghai suddenly shouted, like he was crazy.
It s just a bunch of beasts, what can I do Chu Xiang walked in does medicare pay for prescribed cbd oil front of the crowd, dragging the golden pot in his hand, making a domineering gesture Squeaky Just when Chu Xiang the strongest melatonin took the challenge, there were countless screams in the space.
This kid is really weird, hahaha, he actually wants to rely on his physical strength to attack, doesn t cbd health benefits chart User Guide he think he can t win, and then want to be cbd health benefits chart User Guide funny I want thc and melatonin to use this method to gain cbd health benefits chart User Guide attention.
This Can You Get High Off Cbd Oil cbd health benefits chart made Ye Fan very angry, and many people who laughed at them were people who were not very cultivated because of their status as the thirty sixth grade.
In the past, every sect had to pay great effort and price to fight to the end.
In this way, these elders can be rewarded by the sect master.
This kind of person is probably rare in ten thousand years Within the eye of the wind, Ye Fan s smokymountainsk8way.com cbd health benefits chart body floated high in the sky, bathed in holy light.
What a powerful force what. Compared with this kind of power, I am afraid that the entire Big Dipper galaxy does not have any sense of existence.
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Immortal Frozen do cbd gummies help with sleep Feather Ye Fan frowned slightly, because the stronger this Immortal Venerable, the cbd health benefits chart User Guide more he felt the crisis.
Beichen has won ten consecutive victories, and the following battles will be more intense and cbd health benefits chart exciting.
Whoosh, whoosh, whoosh His figure moved quickly in the ancient woods, and the cbd health benefits chart rhinoceros horn was suspended above his head.
He was suppressed, but in the end, he conceded defeat, and Ye how to make cbd oil from hemp seeds Fan won.
This is really the Law of Heaven Seeing cbd health benefits chart the Demon King roaring in pain, all cbd health benefits chart Cbd Dosage For Liver the Can You Get High Off Cbd Oil cbd health benefits chart mana in his body cbd health benefits chart was continuously absorbed cbd health benefits chart by the chains of Heaven, and all the monks cheered.
For such a battle, Ye Fan naturally refused to come.
Ye Fan was stunned for a moment, Hemp Vs Marijuana Cbd cbd health benefits chart and when he heard the sound, it came from is it legal in iowa to buy cbd oil on line the direction cbd overdose gummies of Lihuo Palace.
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He thought that Ye Fan would definitely die, and he won The cultivator laughed loudly, and he could easily kill Ye Fan as soon as he came cbd health benefits chart up, which meant that their cbd health benefits chart judgment was correct.
Boy, what s going on with this tripod and where did it come from Suddenly, an elder stepped forward and questioned Ye Fan.
But what kind of character Ye Fan, he once fought with the Demon King Bo Xun, how could he be influenced by them Besides, the phaseless sword in is nc stores able tosell cbd oil as of today front of me is a hemp for sale online sacred weapon inherited by Immortal Venerable Yunhai, and it is extremely precious.
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After all, this is the mural formation built by Mr.
But after many times of induction and observation, he can now basically confirm that Ye Fan is not accompanied by the elders of Yunhai Xianmen.
The powerful dark demon Hemp Vs Marijuana Cbd cbd health benefits chart cloud came again, can i put cbd oil directly into my eye for cataract suppressing the top can i put cbd oil directly into my eye for cataract Cbd Manufacturing of can i put cbd oil directly into my eye for cataract Cbd Manufacturing everyone s heads.
If I get it, I can use it to find the seven major Horcruxes.
The five Danxia Sect disciples fell to the ground, burnt all over their bodies, extremely miserable.
Ye Fan, a small second level cultivator, actually defeated the can k9 units smell cbd gummies head of Xuanyun Sect.
Seeing that the patriarch did not move, Cui Zhonghai quickly winked at the third elder and others.
Xuanyunmen, you will definitely lose, it cbd health benefits chart is estimated that you will not even pass the first round Xiao Chen shouted through gritted teeth.
If you just fight, there will be no order at all.
Although this great formation of mountains and rivers is a bit tricky, for Ye Fan, it is also a piece of cake, and he never worries about bolt cbd gummies breaking the formation.
Ye Fan uses his body to resist, which is too exaggerated.
Countless surviving cbd health benefits chart User Guide sects and monks came here to see Ye Fan off.
You Hearing this, it was Xiao Shaolong s weakness.
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Treating them in this way is humiliating.
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They look at cbd health benefits chart User Guide me, I look at you, and they don t know what the silver light and shadow cbd health benefits chart are talking about At this time, Chu Xiang stepped forward. What game did you say he asked.
Suddenly, the eighty one formations released light at the same time.
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Chu Mengyao did not respond, and did not kill Ye Cbd Oil For Skin Rash can i put cbd oil directly into my eye for cataract Fan.
Now it is really difficult for them to take action.
Ye Fan, you kid, you are so disrespectful to the ancestor, does using cbd oil for sleep cause positive ua it s really damn Although he didn t dare to do it, it s still okay to show solidarity.
The third elder s Yin Yang Promise Formation has already cultivated this method can i put cbd oil directly into my eye for cataract Cbd Manufacturing to a very cbd health benefits chart high level.
Boom Endless energy fluctuations are constantly fighting around, like a landslide.
The royal family pulls the cart, which shows the super strength of the royal family.
If it weren t for them, Ye Fan would not have gained so much.
In this way, it means that the threat to Shimen is not big enough, and the Golden Armor will naturally not attack.
After a while, they came under the peak. Senior Brother Chu, someone must have been here, the female cultivator said.
can i put cbd oil directly into my eye for cataract The three elders told everything one by one, cbd health benefits chart but covered up a lot of facts.
55 Evidence-Based Benefits of CBD Oil (Plus Side-Effects)
Stay up to date with what the medical research is saying about some of the common applications for CBD.
All articles are evidence-based, written by qualified health professionals, and use peer-reviewed scientific research for any and all sources.
There are few supplements with as many health benefits as CBD.
Millions of people use it on a daily basis to support symptoms ranging from chronic pain to anxiety.
Learn about the many benefits of CBD with this exhaustive list of 55+ evidence-based benefits of CBD.
This is a huge topic, so feel free to jump around to the sections that are most relevant to you.
Table of Contents
- Quick Overview: What Are the Benefits of CBD?
- 1.1 CBD For Arthritis Pain
- 2.1 CBD For Anxiety
- 3.1 CBD For Acne
- 4.1 CBD For Epilepsy
- 5.1 CBD For Inflammatory Bowel Disease (IBD)
- 6.1 CBD For High Blood Pressure
- 7.1 CBD For Premenstrual Syndrome (PMS)
- 8.1 CBD For Diabetes
Quick Overview: What Are the Benefits of CBD?
CBD has a few core benefits that make it useful for a wide range of different symptoms.
For example, the robust anti-inflammatory profile of CBD oils makes it useful for many different inflammatory disorders, including multiple sclerosis, Crohn’s disease, arthritis, migraine headaches, and more.
Here are some of the core benefits CBD that make it effective for a myriad of health conditions:
- Alleviates pain & inflammation
- Supports mental health & wellbeing
- Supports healthy skin
- Protects the brain
- Supports digestive function
- May protect the cardiovascular system
- Supports reproductive health
- Regulates hormones & metabolism
Cannabinoid Benefits Chart
CBD isn’t the only active ingredient that contributes to the overall health benefits of a hemp extract.
While CBD is the main ingredient, other cannabinoids and cannabis-derived terpenes contribute to the overall health benefits of a full-spectrum CBD oil as well.
Here’s a brief overview of the many health benefits of cannabinoids:
|Health Benefit||CBD (Cannabidiol)||THC (Tetrahydrocannabinol)||CBN (Cannabinol)||CBG (Cannabigerol)||CBC (Cannabichromene)||THCV (Tetrahydrocannabivarin)|
1. Alleviates Pain & Inflammation
Cannabis products have been used to relieve chronic pain and inflammation for thousands of years.
Only recently have scientists been able to analyze and understand how hemp and marijuana plants can offer so many benefits for pain symptoms.
The benefits of CBD oil for pain include:
- Reduces inflammation
- Alleviates common side-effects of pain
- Supports nerve cell health
- Activates pain receptors in the spinal cord and brain
1.1 CBD For Arthritis Pain
There are two types of arthritis — osteoarthritis and rheumatoid arthritis. CBD has been shown to support both through its anti-inflammatory, painkilling, and tissue-restorative benefits.
There are dozens of studies available that cover the effects of CBD for arthritis. Most of this research has shown promising results using both topical CBD pain creams and CBD oils for arthritis.
The benefits of CBD oil for arthritis include:
- Alleviates underlying inflammation
- Relieves chronic pain
- Prevents T-cell infiltration in rheumatoid arthritis
- Promotes recovery of the joint tissue
Evidence: CBD & Arthritis
Animal studies involving mice with collagen-induced arthritis treated with CBD showed a dramatic improvement in pain symptoms in the mice given CBD compared to the control group [Malfait 2000].
Rheumatoid arthritis (RA) is an autoimmune disease. This means that the cause of joint pain with this type of arthritis comes from the body’s own immune cells attacking and destroying the cells that make up the joint tissue. This leads to pain, inflammation, and swelling. A type of immune cells called T-cells is responsible for attacking and destroying the joints.
CBD has been shown to inhibit T-cell infiltration in rheumatoid arthritis joint tissue [Specter 1990]. Other studies have shown that CBD was able to also prevent T-cells from attacking the joints [Klein 1991].
CBD has also been shown to block key inflammatory messengers involved with rheumatoid arthritis — such as nitric oxide, TNF-a, IL-1, IFN-g, and much more [Coffey 1996, Watzl 1991].
1.2 CBD For Fibromyalgia
Fibromyalgia is a common condition (affecting up to 2% of the population) that involves chronic pain, fatigue, insomnia, depression, and poor focus.
There’s no cure for fibromyalgia, and most of the current medications available for treating it aren’t very effective.
The benefits of CBD oil for fibromyalgia include:
- Alleviates chronic pain
- Improves sleep quality
- Alleviates side effects such as anxiety & depression
Evidence: CBD & Fibromyalgia
There hasn’t been a lot of research on the effects of CBD on fibromyalgia. A 2018 systematic review on CBD for pain only found seven studies involving CBD or other cannabinoids for the treatment of fibromyalgia, and evidence was limited for each of these studies [Stockings 2018].
With that said, there is plenty of evidence for the painkilling benefits of CBD for other types of neuropathic pain. While more research is needed, the benefits of CBD oil for managing tough to treat pain involved with fibromyalgia are promising.
There are also some studies on the effects of synthetic cannabinoids on pain, but the results are much less impressive than CBD in its natural form. A large meta-analysis done by the Cochrane Group (considered the highest level of research) analyzed two clinical studies that explored the effects of a synthetic cannabinoid called nabilone for fibromyalgia [Walitt 2016]. This study reported no significant improvement using the synthetic cannabinoid.
1.3 CBD For Migraine Headaches
Migraines are a severe form of headaches. They’re often accompanied by symptoms such as nausea, vomiting, or sensitivity to light, sound, or smell.
Many people are reaching for a bottle of CBD oil for migraine headaches instead of prescription painkillers. There’s even some evidence to suggest CBD may offer a preventative action against migraine attacks.
The benefits of CBD oil for migraine headaches include:
- Relieves inflammation
- Blocks the transmission of pain
- May prevent the release of serotonin from platelets
- May reduce vascular spasms
Evidence: CBD & Migraines
Migraine headaches are poorly understood despite recent advancements in neurology.
There are a few theories for what causes migraine headaches:
- Excessive serotonin release from platelet cells
- Spasms of the arteries feeding blood to the brain
There are no clinical studies explicitly exploring the impact of CBD on migraines, but there are a few studies that suggest CBD as a promising candidate for treatment.
CBD has been shown to inhibit serotonin release from platelet cells in the brain [Volfe 1985], block inflammation in the brain [Ryberg 2007], and inhibit pain signals directly.
More loosely, CBD may prevent vascular spasms in the brain through its antispasmodic effects and the ability to upregulate GABA. GABA is responsible for inhibiting glutamate, which has been linked with muscle spasms of the arteries feeding the brain.
1.4 CBD For Nerve Pain (Neuropathic Pain)
Nerve pain is any pain originating from damage or dysfunction of the nerve cells themselves. This type of pain is notoriously difficult to treat — up to 60% of patients suffering from neuropathic pain can’t find an effective treatment.
There’s been a lot of promising research in recent years around the use of CBD oil for nerve pain. It works by targeting a system called the endocannabinoid system (ECS) — which is responsible for regulating the health of the nerve cells.
It’s thought that this effect on the endocannabinoid system is the primary mechanism CBD uses to block pain originating in the nerves. However, more research is needed to understand this effect in more detail.
The benefits of CBD oil for nerve pain include:
- Offers a protective action on the neurons
- Promotes neuroregeneration
- Blocks pain transmission in the spinal cord and brain
- Promotes GABA activity in the neurons
Evidence: CBD & Nerve Pain
A study involving 303 patients diagnosed with treatment-resistant peripheral nerve pain were given a topical spray consisting of CBD and THC [Serpell 2014]. The study concluded that the CBD/THC spray improved the sleep quality and severity of pain in a significant portion of the treatment group.
1.5 CBD For Muscle Pain & Recovery (Delayed Onset Muscle Soreness)
Delayed onset muscle pain (DOMS) is a normal part of working out. It happens when we push our muscles harder than they’ve worked before, or in a way we’re not used to. The stress placed on the muscle fibers leads to damage and inflammation, which can result in aches and pains.
DOMS usually appears 24 – 48 hours after a workout and can last for several days at a time.
This form of muscle pain can make it difficult to get back into the gym until the pain goes away.
CBD is a useful supplement for alleviating the pain and inflammation with DOMS, helping you recover quicker and get back in the gym as soon as possible.
The benefits of CBD oil for muscle pain include:
- Relaxes tight muscle fibers
- Blocks pain transmission traveling from the muscles to the brain
- Alleviates inflammation in the muscles
- Improves sleep quality and recovery
- Enhances satellite cell differentiation in the muscles
- Supports protein synthesis by reducing cortisol levels
Evidence: CBD for Muscle Pain & Recovery
While there’s plenty of evidence to suggest CBD products can be used to reduce inflammation and ease the pain — there are no specific studies exploring the benefits of CBD products for DOMS or other forms of muscle pain in humans.
Animal studies have shown doses of CBD can effectively reduce various forms of chronic muscle pain [Wong 2019].
1.6 CBD For Sickle Cell Anaemia
Sickle cell anemia is a condition involving misshapen red blood cells. The shape often appears to have a sickle-like shape, which is where the name for the disease originated.
One of the hallmark signs of sickle cell anemia is chronic pain. The shape of the blood cells makes it difficult for them to fit into some of the small capillaries lining the skin’s surface, in the muscles, and throughout the internal organs. When these cells become stuck, they can lead to pain and inflammation that’s notoriously difficult to treat.
While there’s some research on the effects of CBD for sickle cell anemia pain so far, the research is still in its infancy.
The benefits of CBD oil for sickle cell anemia include:
- Alleviates pain
- Inhibits inflammation
- Stabilizes mast cells to prevent inflammation & irritation
Evidence: CBD & Sickle Cell Anemia
Animal studies involving the pharmaceutical preparation of the cannabinoids CBD and THC — called Sativex — has been shown to dramatically reduce pain and inflammation associated with sickle cell anemia [Vincent 2016].
This study reported the primary mechanism of action for the painkilling effects of CBD was through inhibition of mast cells. These cells become activated when blood cells become lodged in the capillaries — leading to a cascade of inflammation and pain.
2. Supports Mental Health & Wellbeing
Mental illness covers a wide range of health conditions — from depression and anxiety to psychosis and schizophrenia.
CBD offers several distinct benefits for mental health that make it useful for a variety of unrelated mental health conditions. I should note that CBD is not an approved treatment for any mental health issue. It helps supports mental health and wellbeing when used in combination with other therapies. This usually includes diet and lifestyle changes, professional counseling, or other supplements and medications.
If you’re experiencing any severe mental health symptoms, it’s important you visit a medical professional as soon as possible before turning to natural health supplements like CBD.
The main benefits of CBD for mental wellness include:
2.1 CBD For Anxiety
Anxiety is one of the most common mental health conditions in the world. In the United States, anxiety affects roughly 18% of the population at any given time.
CBD oils offer several key benefits for managing, mitigating, and even treating different types of anxiety conditions.
The benefits of CBD oil for anxiety include:
- Boosts GABA function in the brain
- Regulates serotonin & dopamine activity
- Relaxes tight or tense muscles
- Alleviates inflammation in the brain
- Promotes a more restorative sleep
- Reduces cortisol levels
Evidence: CBD & Anxiety Disorders
A preclinical study published in 2015 explored CBD’s potential to treat several prominent forms of anxiety disorders [Blessing 2015].
The study concluded that there was conclusive evidence demonstrating the efficacy of CBD for reducing anxiety disorders such as PTSD, generalized anxiety disorder, obsessive-compulsive disorder, and social anxiety disorder.
A large meta-analysis published in 2018 highlighted the benefits of CBD oil for post-traumatic stress disorder (PTSD) [Bitencourt 2018]. The study explored the results of animal studies and clinical trials. The study concluded that CBD significantly improved symptoms of PTSD — including the retention of unpleasant memories. The doses used in this research ranged from 12 mg (orally) to 10 mg/kg (injected).
2.2 CBD For Chronic Stress
Stress is an entirely normal and healthy process — but only in small bursts. Being stressed out all the time can be damaging to our health long-term.
Chronic stress can lead to high blood pressure, low immunity, autoimmune disease, chronic fatigue syndrome, metabolic disorders, anxiety disorders, depression, and much more.
One of the primary benefits of CBD is its ability to promote relaxation and alleviate chronic stress.
The benefits of CBD for stress include:
- Improves hypothalamic function
- Protects the body from oxidative damage
- Promotes “rest and digest”
- It helps manage common side effects of stress
Evidence: CBD & Chronic Stress
Cortisol is the primary stress hormone in the human body. Cortisol testing is considered one of the simplest ways to measure stress levels in humans, and reducing cortisol is a key therapeutic target for managing chronic stress levels.
In one study, 11 human volunteers were given high-dose CBD (up to 600 mg CBD) to measure its effects on cortisol levels [Zuardi 1993]. Blood tests were used to measure cortisol levels before and after taking CBD. The results showed a substantial reduction in cortisol levels after taking CBD extract on two separate occasions.
2.3 CBD For Insomnia & Sleep Disorders
There are two main types of insomnia — sleep onset insomnia (difficulty falling asleep) and sleep maintenance insomnia (inability to stay asleep throughout the night).
Research supports the use of CBD for both forms of insomnia — it helps users fall asleep faster, stay asleep longer, and feel more refreshed the following morning.
The benefits of CBD oil for insomnia include:
- Sedative qualities promote faster sleep onset
- May reduce nightmares
- Regulates the sleep cycle and sleeping patterns
- Alleviates common causes of insomnia
Evidence: CBD & Insomnia
A meta-analysis exploring the effects of CBD on sleep dating back from the 1970s found that CBD has a different impact on sleep, depending on the dose [Babson 2017].
Low-dose CBD has a mild stimulating effect, while high-doses have a much stronger sedative action. High doses of CBD was associated with increased total sleep time and decreased incidence of movement or disruptions throughout the night.
The same meta-analysis also suggested improvements in sleep quality for people suffering from REM sleep behavior disorder — a condition that causes sufferers to act out during deep REM sleep.
2.4 CBD For Mood Disorders
The term “mood disorder” refers to any neurological disorder that affects the body’s ability to regulate or maintain emotion.
There are dozens of mood disorders, and CBD has a unique effect for each one.
CBD has been shown to help with bipolar disorder, depression, mania (with caution), hypomania, and seasonal affective disorder (SAD).
The primary benefits of CBD oil for mood disorders include:
- Inhibits inflammation in the brain
- Alleviates common side effects of mood disorders
- Regulates serotonin and dopamine activity
Evidence: CBD & Mood Disorders
Animal studies using well-established models for depression have shown CBD has a dramatic improvement in depression scores compared to placebo control groups [Réus 2011].
Other studies have elucidated how CBD is able to alleviate depression. One study found that CBD extracts were able to increase serotonin activity in mice [Sales 2018]. Serotonin is one of the primary targets for pharmaceutical antidepressant medications including Sertraline and Prozac.
CBD has also been shown to alleviate obsessive behaviors in mice — measured by marble-burying habits in mice [Casarotto 2010].
2.5 CBD For Addiction
Addiction and substance abuse to both illicit and prescription medications is a serious problem around the world. In the United States alone, it’s estimated that 21 million people have at least one addiction.
Typical forms of addiction include — substance abuse, gambling addiction, or sex addiction.
Addiction is classified as a mental disorder by the American Psychiatric Association. It’s characterized by a compulsive desire to do something despite having clear negative impacts on the body.
The benefits of CBD oil for addiction include:
- Regulates the function of dopamine in the brain
- Alleviates common symptoms of drug withdrawal syndromes
- CBD may reduce cravings for tobacco
Evidence: CBD & Addiction
CBD has been shown to reduce cigarette cravings in long-term smokers [Morgan 2013]. The study concluded that 40% fewer cigarettes were smoked by participants in the treatment group than the placebo control group. The effects of CBD had a persistent impact for several weeks after the study concluded.
A study published in 2019 analyzed a group of 146 medical marijuana patients who were also taking benzodiazepine medications [Purcell 2019]. Researchers reported that 30% of patients were no longer using the drugs at the two-month follow-up period. At the 6-month mark, 45% of patients taking part in the study were no longer using benzodiazepines. Researchers conducting this study associated cannabis use as one of the key factors that help patients break free from the addictive tendencies of long-term benzodiazepine use.
Many people are using CBD oil to wean off Xanax and other benzodiazepine drugs. It’s been shown to offer direct support for the underlying cause of benzodiazepine withdrawal by preventing the reuptake of GABA [Banerjee 1975]. This is the target neurotransmitter for benzodiazepine anti-anxiety medications.
2.6 CBD For Schizophrenia
The benefits of CBD for schizophrenia are not well understood. Research has a long way to go before making any conclusive claims about using CBD to support the condition.
With that said, CBD has been shown to offer several key benefits that suggest it as a promising candidate for managing symptoms of the condition.
The suggested benefits of CBD oil for schizophrenia include:
- Regulates serotonin, dopamine, and glutamate
- Improves blood flow to cortical regions of the brain
- Alleviates common side effects of schizophrenia
- Regulates anandamide levels
Evidence: CBD & Schizophrenia
The research for the effects of CBD on schizophrenia is still in the early stages. There are many challenges in finding effective treatment options for this condition due to its complexity. There isn’t one specific cause for the condition, and most of the likely causes are only theoretical.
The prominent theories for the causes of schizophrenia include:
- Anandamide excess
- Dopamine excess
- Glutamate excess
- Poor blood flow to cortical regions of the brain
One of the best studies we have available on CBD’s potential benefits for schizophrenia compared the use of CBD with current prescription antipsychotic medications [Leweke 2012]. This double-blind, placebo-control study found that CBD was as effective as amisulpride for treating schizophrenia symptoms.
Amisulpride is a potent second-generation antipsychotic drug used in the treatment of schizophrenia and psychosis.
Researchers conducting this study suggested the mechanism of action for CBD was through improved anandamide signaling.
Other studies have shown another cannabinoid, THC (tetrahydrocannabinol), activates CB1 receptors in the brain [Pertwee 2008], which are considered vital mediators of psychosis. Products containing more than trace amounts of THC should be avoided by anybody diagnosed or at risk of developing schizophrenia.
3. Supports Healthy Skin
Skin is the largest organ in the body. It’s responsible for maintaining our internal body temperature, protecting our internal organs, storing nutrients, and manufacturing vitamin D.
CBD offers a similar level of benefit for many different skin conditions — ranging from inflammatory conditions like psoriasis or eczema to cosmetic disorders like acne or wrinkling.
3.1 CBD For Acne
Acne is caused by an overproduction of sebum, which promotes bacterial growth inside of the pores. This leads to inflammation, swelling, and redness around the pore.
CBD oil and CBD skincare products offer similar benefits against the formation of acne.
CBD topicals provide a direct dose of CBD to the surface of the skin, while CBD oils are better for alleviating many of the underlying causes for acne (such as inflammation or excess oil production).
The benefits of CBD oil for acne include:
- Reduce redness & inflammation
- Regulates oil production in the skin
- Makes sebum less-viscous
- Inhibits bacterial growth in the pores
Evidence: CBD & Acne
A study exploring the potential anti-acne effects of cannabinoids noted the most significant improvement came from the novel cannabinoid THCV (tetrahydrocannabivarin) [Oláh 2016].
CBD and CBDV also showed dramatic improvements in controlling sebum production, reducing inflammation, and activating vanilloid receptors in the skin. Each of these effects contributes to the overall anti-acne benefits of a full-spectrum CBD extract.
3.2 CBD For Psoriasis
Psoriasis is a skin condition caused by an autoimmune disorder that causes rapid regeneration of skin cells. This leads to characteristic itchy, red, scaly patches that can form anywhere on the body.
There’s no cure for this condition. Most patients experience cycles of flare-ups and remissions — each lasting several weeks or months at a time.
CBD has been shown to offer three distinct benefits for managing or preventing the symptoms of psoriasis. Topical products that contain high concentrations of CBD may be useful for reducing the severity of the condition and preventing flare-ups before they occur.
The benefits of CBD for psoriasis include:
- Regulates excessive skin cell growth
- Inhibits inflammation
- Helps manage pain associated with psoriasis
Evidence: CBD & Psoriasis
A study published in 2013 found a set of cannabinoid receptors located in the skin could reduce excessive skin cell growth associated with psoriasis [Ramot 2013]. Due to the ability for CBD to regulate these receptors, researchers suggested topical CBD products may be able to inhibit the formation of psoriasis patches on the skin.
Another study found that CBD directly inhibits an inflammatory messenger molecule known as nuclear factor-kappa-b (NFkB) [Silva 2019] — which is considered one of the primary inflammatory mediators involved with the formation of psoriasis.
3.3 CBD For Eczema
Eczema is an inflammatory disorder affecting the outer layers of the skin (epidermis). Rough, dry patches caused by eczema can be extremely itchy and painful.
The benefits of CBD oil for eczema include:
- Alleviates pain and itchiness in the skin
- Inhibits inflammation in the skin
Evidence: CBD & Eczema
A clinical study consisting of 20 patients with inflammatory skin disorders (psoriasis or eczema) were given a topical CBD cream and instructed to apply it twice per day for three months [Palmieri 2019]. At the end of the study, researchers reported a significant improvement in the inflammatory status of the skin for both conditions after using CBD ointment.
4. Protects The Brain (Neuroprotective)
CBD is a neuroprotective agent — which means it can preserve the function and structure of the neurons that make up the central nervous system.
These specialized cells are highly sensitive to damage from oxidative or inflammatory compounds. Autoimmune disease, prion disease, genetic polymorphisms, and more can all lead to neuronal damage. The umbrella term for these conditions is neurodegenerative disorders — which refers to any condition that involves gradual destruction or loss of nerve cells.
Traumatic brain injuries or traumatic spinal cord injuries can also lead to the destruction of the nerve cells. This can eventually lead to mood disorders, difficulty concentrating, loss of motor function, and much more.
CBD has a lot of benefits for neurological disorders through its anti-inflammatory and endocannabinoid-mediated effects.
This system is one of the primary regulators for nerve cell health. It protects the nerves from damage, supports nerve cell regeneration, and maintains optimal cell function.
4.1 CBD For Epilepsy
The neuroprotective effect of CBD is especially apparent when looking at the benefits this compound has for epileptic disorders.
Several large-scale clinical trials have explored the effects of CBD extracts (both full-spectrum and pure CBD) for treating various forms of epilepsy — including Dravet’s syndrome, Lennox-Gastaut Syndrome, childhood absence epilepsy, and more.
CBD has been shown to dramatically reduce the severity of epileptic seizures and seizure frequency (how often a seizure occurs).
The benefits of CBD for epilepsy include:
- Alleviates convulsions
- Protects the nerve cells
- Modulates key receptors that regulate brain health
- Alleviates neuro-inflammation
- Supports GABA activity
Evidence: CBD & Epilepsy
A 2018 meta-analysis involving 670 people found that 71% of people given full-spectrum CBD extracts experienced reduced seizure frequency compared to placebo [Pamplona 2018]. Only 46% of patients taking CBD isolates reported improvements — suggesting that the other compounds in a full-spectrum extract contribute to the antiepileptic effects of CBD.
Researchers reported that 40% of people in the study experienced half the amount of seizures as expected, a quarter had a 70% drop in seizure frequency, and 10% were seizure-free by the end of the study.
4.2 CBD For Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease involving the destruction of the myelin sheath around nerve cells. You can think of your nerve cells like a bundle of wires and the myelin as the plastic insulation. Without myelin, nerve cells can’t transmit messages to the rest of the body.
There is no cure for MS, but there are a few medications that can be used to slow the progression of the disease.
CBD is a popular option for managing MS because it targets several underlying causes of the condition (inflammation, autoimmunity, nerve cell function) and alleviates the most common side effects (pain, muscle spasms, bladder control).
A new pharmaceutical medication for MS is derived from CBD and the related cannabinoid, THC — called Sativex®
The benefits of CBD for multiple sclerosis include:
- Resists the development of autoimmunity
- Reduces neuroinflammation
- Keeps T-cells from congregating around the nerves
- Reduces muscle spasms
- Supports bladder control
- Alleviates nerve pain
Evidence: CBD & Multiple Sclerosis
Most of the research on the effects of CBD products for multiple sclerosis comes from a pharmaceutical preparation called Sativex®. Sativex® is a 1:1 extract of CBD and THC and the only cannabis-related drug approved for treating MS in the United States.
Clinical trials on Sativex® have shown the drug can directly improve many of the common side effects of multiple sclerosis. It’s been shown to improve muscle spasms [Wade 2010], bladder dysfunction [Brady 2004], and nerve pain [Barnes 2006].
4.3 CBD For Huntington’s Disease
Huntington’s disease is a genetic disorder affecting the brain. There’s no cure for the disease, but there are a few ways to slow its progression and alleviate the most common side effects.
The underlying cause of Huntington’s disease is a gradual buildup of a protein called Huntington — which can lead to the eventual damage and destruction of the nerve cells in the brain. This leads to uncontrollable muscle movements, inability to control emotions, and a gradual reduction in cognitive function.
CBD has several key benefits to offer Huntington’s disease patients. The benefits primarily rely on its potent anti-inflammatory and neuroprotective benefits.
The benefits of CBD oil for Huntington’s disease include:
- Reduces inflammation in the brain
- Alleviates common side effects of Huntington’s disease
- Offers powerful neuroprotective benefits
Evidence: CBD & Huntington’s Disease
There’s a lack of research on the effects of CBD on Huntington’s disease. Most of the research available uses animal models or small study groups. However, the research currently available shows a lot of promise towards CBD as a potential new therapy to help patients manage symptoms.
Experimental models of Huntington’s disease in animals have shown dramatic improvements in symptoms and disease progression after being treated with a combination of CBD and THC (Sativex®) [Sagredo 2011].
Case reports published in Oxford Condition Monographs have also suggested success among Huntington’s disease patients using CBD to manage symptoms like chorea (involuntary eye movement) and speech difficulties [Bates 2014].
4.4 CBD For Parkinson’s Disease
Parkinson’s disease (PD) is a chronic neurodegenerative disorder affecting the nucleus accumbens (NA) — which is where most of the brain’s dopamine is produced.
Over several years, dopamine levels in the brain start to decline, resulting in side effects like poor concentration, muscle tremors, depression, apathy, sleep disorders, and much more.
CBD is useful for supporting this condition but can’t be used to cure it — there’s are currently no cure for this condition. Instead, supplements and medications are used to slow disease progression, ease common side effects, and improve quality of life.
The benefits of CBD oil for Parkinson’s disease include:
- Reduces neuroinflammation
- Alleviates common side effects
- May improve dopamine production
- Supports healthy microbiome diversity
Evidence: CBD & Parkinson’s Disease
One of the hallmark side effects of Parkinson’s disease is muscle tremors and loss of muscle coordination. CBD was shown to significantly reduce muscle tremors associated with Parkinson’s disease in animal models [Kluger 2015].
Some of the more interesting research on the potential benefits of CBD for Parkinson’s disease have shown that CBD may be able to boost dopamine levels in the brain [Morales 2018]. These findings are significant because the primary cause of symptoms associated with Parkinson’s disease is a gradual reduction of dopamine in the brain. More research is needed to understand how this effect applies to real-life patients, but the research so far is promising.
A small clinical study involving the use of CBD for patients experiencing psychotic side effects found the supplement had a significant reduction in the severity of symptoms [Zuardi 2009]. This study reported no adverse side effects from the CBD throughout the study period.
4.5 CBD For Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic lateral sclerosis (ALS) — AKA Lou Gehrig’s disease — is a neurodegenerative condition involving the breakdown of the neurons responsible for controlling muscle movement (motor neurons).
There’s no cure for this condition, and the treatment options are limited. The current treatment approach for this condition is to alleviate side effects, slow the progression of the disease, and improve quality of life.
CBD is not a cure for ALS, but it may support patients with side effects such as pain, muscle cramping, insomnia, anxiety, and depression.
The benefits of CBD oil for ALS may include:
- Alleviates chronic pain
- Relaxes the muscles
- Supports sleep onset
- May slow the progression of the disease by supporting neuron health
Evidence: CBD & ALS
There are currently no clinical trials in the academic literature that explore the direct impact of CBD extracts with ALS. The only evidence available for the benefits of this supplement comes from anecdotal reports of patients using CBD products to manage symptoms and implied benefits from other research (such as benefits on sleep, pain, and muscle spasms).
Animal studies have been done to explore the impact of another cannabinoid, THC, on ALS. In a study published in 2004, researchers reported mice with experimental ALS had significantly less severity in their symptoms after being treated with THC [Raman 2004].
5. Supports Digestive Health
Digestive problems are prevalent — experts estimate that nearly one in five people suffer some form of digestive dysfunction.
Poor digestive health can affect nearly every other organ system in the body. Chronic inflammation can cause particles to “leak” into the bloodstream, interfering with hormones, neurotransmitters, or organ function elsewhere in the body.
Additionally, chronic inflammation in the gut can spill into the bloodstream and trigger inflammation in the lungs, brain, skin, and more.
CBD offers several benefits for digestive health, but the most significant impact, by far, is its ability to inhibit inflammation.
Inflammation is a key underlying cause of digestive problems. Inflammation may be caused by irritants in food, allergies, alterations in the gut microbiome, or genetic polymorphisms.
5.1 CBD For Inflammatory Bowel Disease (IBD)
Inflammatory bowel disease (IBD) refers to two conditions — ulcerative colitis (UC) and Crohn’s disease.
Both conditions involve chronic inflammation in the digestive tract that leads to problems with absorption, constipation or diarrhea, altered gut microflora, pain, and cramping.
CBD offers direct benefits towards IBD by inhibiting inflammation, alleviating pain, and supporting the regeneration of damaged cells in the gut lining. The most popular ways of using CBD for IBD are CBD oils and CBD suppositories.
- Inhibits inflammation in the digestive tract
- Prevents mast cell activation
- Alleviates pain
- May support microbiome diversity
Evidence: CBD & IBD
A review article published in 2013 highlights several in-vitro and animal studies that showed CBD could inhibit several different forms of inflammation most commonly found with inflammatory bowel disease [Esposito 2013].
The study concluded that “[CBD] possesses an extraordinary range of beneficial effects that may slow the course of the disease, ameliorate symptoms and potentially increase the efficacy of the drugs available for the therapy of invalidating gut disorders such as ulcerative colitis or Crohn’s disease.”
Another study analyzed the results of three small clinical trials exploring the effects of CBD for Crohn’s disease [Kafil 2018]. Patients receiving CBD oil were asked to fill out a questionnaire to determine their quality of life. The study found patients using CBD had scores that were roughly 17% higher than participants in the placebo control group.
More large-scale clinical trials are needed to fully understand the benefits of CBD oil in the treatment of inflammatory bowel disease.
5.2 CBD For Irritable Bowel Syndrome (IBS)
Irritable bowel syndrome (IBS) has symptoms similar to IBD — diarrhea or constipation, abdominal pain, nausea, gas and bloating, fatigue, and weight gain or loss.
The difference between IBS and IBD is that there’s no identifiable cause for the condition with IBS. It’s classified as a syndrome rather than a disease, which means it’s a collection of related symptoms rather than a specific disease process.
Not knowing what’ the specific cause for the condition makes IBS challenging to diagnose and treat. Doctors diagnose the condition only after ruling out other causes for the associated symptoms.
CBD is a popular supportive option to manage symptoms, and there’s some interesting research that suggests a potential cause for IBS is a dysfunction of the endocannabinoid system itself.
The benefits of CBD for irritable bowel syndrome include:
- Alleviates anandamide deficiencies
- Reduces inflammation in the gut
- Alleviates cramping and hyperactive intestinal movement
- Reduces appetite
Evidence: CBD & IBS
The research on the benefits of CBD for IBS is still in its infancy — the main mechanisms suggested for CBD products are only in the experimental phase. So far, the results have been promising and offer a compelling reason to conduct larger, more expensive studies on the interaction.
The underlying cause of IBS is not well understood. In recent years, a theory has surfaced that suggests anandamide deficiency as a key factor in the condition [Russo 2016]. Anandamide is a key component of the endocannabinoid system used to regulate nerve and epithelial cell function in the digestive tract. This is also thought to be a potential cause for migraine headaches and fibromyalgia — two common comorbidities in IBS patients.
CBD has been shown to regulate anandamide levels by activating the vanilloid VR1 receptors responsible for controlling the breakdown of this endocannabinoid [Bisogno 2001]. By regulating this receptor, it’s thought that CBD can increase anandamide levels in the gut, thus reducing IBS symptoms.
5.3 CBD For Nausea
CBD is one of the most reliable anti-nausea herbal extracts available. It works directly on the medulla oblongata, where the nausea center is located.
People are using CBD to alleviate nausea experienced from a hangover while traveling (motion sickness), as a side effect of medications or cancer therapy, morning sickness, and much more.
The benefits of CBD oil for nausea include:
- Increases anandamide levels in the medulla oblongata
- Alleviates inflammation
- Relaxes muscle cramping and pain
Evidence: CBD & Nausea
A study exploring the antiemetic (anti-nausea) benefits of cannabinoids reported that both CBD and THC offer potent anti-nausea effects — but through separate mechanisms [Parker 2011].
THC alleviates nausea symptoms by activating the CB1 receptors of the endocannabinoid system directly. These receptors are responsible for regulating the 5HT3 serotonin receptors that control the urge to vomit. CBD works indirectly by regulating a different type of serotonin receptor (5HT1A), which leads to reduced serotonin in the nausea center — leading to suppression of the nausea reflex.
6. May Protect the Cardiovascular System
Cardiovascular disease is the number one killer in the developed world. This critical system is highly susceptible to inflammation and free-radical damage.
There are many different types of cardiovascular disease — such as hypertension, coronary artery disease, arrhythmias, stroke, chronic obstructive pulmonary disease, or congestive heart failure.
The benefits of CBD oil for heart disease include:
- Stabilizes blood sugar levels
- Promotes weight loss
- Reduces inflammation
- Lowers blood pressure
- Protects against oxidative damage
6.1 CBD For High Blood Pressure
Anything higher than 120/80 mmHg is considered high blood pressure. The medical condition “hypertension” is diagnosed when blood pressure exceeds 130/90 mmHg.
Hypertension can lead to severe long-term consequences if it goes unchecked for too long. It can increase the chances of developing other cardiovascular disorders — such as atherosclerosis, arteriosclerosis, coronary artery disease, or stroke.
CBD oil is a popular natural health supplement to help with the early stages of high blood pressure. However, due to potential adverse interactions between CBD and blood pressure medications, you should always speak with your doctor before using CBD products to help manage your condition.
The benefits of CBD oil for hypertension include:
- Relaxes the blood vessels
- Alleviates anxiety
- Reduces inflammation in the arteries
Evidence: CBD & Hypertension
A randomized crossover study found a single dose of CBD (600 mg orally) in hypertensive patients resulted in a reduction in resting blood pressure [Jadoon 2017]. This effect was primarily associated with the supplement’s anti-anxiety effects — which is a common cause for high resting blood pressure.
An experimental study using constricted human arteries exposed to CBD extract found a reduction of arterial pressure by 40% [Stanley 2013].
Follow-up studies found the mechanism CBD uses to reduce blood pressure relied on a modulation of the CB1 endocannabinoid receptors (found throughout the cardiovascular system) [Stanley 2015]. The CB1 receptors triggered nitric oxide release, which is a potent vasodilator (widens the arteries to reduce blood pressure).
6.2 CBD For Stroke
A stroke is a disease affecting the arteries supplying blood and nutrients to the brain. When blood vessels become blocked or rupture, the blood can’t reach various parts of the brain. Within minutes, a lack of blood flow results in the death of the affected neurons.
Strokes can lead to severe, long-term neurological deficits if not treated immediately.
CBD is not a treatment for stroke but offers benefits that may reduce your chances of developing a stroke or increase chances of survival and recovery.
The benefits of CBD oil for stroke include:
- Protects the neurons
- Resists hypoxic damage
- May improve blood flow to the brain
- Alleviates common underlying causes
Evidence: CBD & Stroke
There aren’t any large clinical trials available to demonstrate the benefits of CBD for stroke patients. However, a few preclinical studies suggest CBD may be a promising candidate as a supportive agent for ischemic injuries caused by stroke.
Animal studies exploring CBD’s protective effects for ischemic injury (injury caused by lack of oxygen) found significantly less lasting damage in animals treated with CBD immediately after the injury [Braida 2003]. CBD appeared to have a protective effect against ischemia.
Other studies on CBD’s benefits for stroke suggest that the majority of effects result from its ability to modulate the CB1 endocannabinoid receptors. These receptors have been shown to provide neuroprotective effects by preventing hyperexcitation of the neurons, supporting the phosphatidylinositol-3 kinase/Akt pathway, and resisting hypothermia [Hayakawa 2010].
6.3 CBD For Atherosclerosis
Atherosclerosis is characterized by a buildup of fatty deposits on the arterial walls. These deposits are made up of cholesterol, various lipids, calcium, and fibrin.
As the plaque develops, the artery walls become thicker — causing reduced blood flow through the artery. This means less blood, oxygen, and nutrients can move through the arteries.
This condition can go unnoticed for many years. When blood flow is reduced too much, it can cause the tissue the blood vessel supports to become hypoxic (lack of oxygen). If this blockage occurs in the large arteries feeding the heart, brain, or extremities, it can lead to severe consequences. A few examples include heart attack, angina, kidney failure, or peripheral artery disease.
CBD has been shown to offer powerful preventative benefits for atherosclerosis by targeting several of its underlying causes.
The benefits of CBD oil for atherosclerosis include:
Evidence: CBD & Atherosclerosis
There’s no clinical research exploring the impact of CBD for atherosclerosis specifically, but there are plenty of studies that suggest CBD as a promising treatment option through its effects on several underlying causes for the condition.
For example, CBD and other endocannabinoid regulators have been shown to reduce blood pressure in rats with induced hypertension [Bátkai 2004]. High blood pressure has been shown to significantly increase the risk of developing atherosclerosis and coronary artery disease later in life [Nakanishi 2017].
CBD has also been shown to activate PPAR [Stanley 2013], which exerts several protective effects against the progression of atherosclerosis [Bishop‐Bailey 2000].
7. Supports Reproductive Health In Men & Women
CBD offers a few unique benefits towards maintaining the health of the reproductive system in both men and women.
While there’s some evidence to suggest CBD can be useful for making intercourse more pleasurable, the most significant improvement comes from its ability to alleviate performance anxiety. Other benefits include its ability to support various health conditions involving inflammation or pain in the reproductive organs.
Most people use CBD oils or suppositories (female reproductive health), but there are also sex-specific products available like CBD lubes and topical oils.
The benefits of CBD for the reproductive system:
- May help alleviate pain during intercourse
- Relieves performance anxiety
- May support erectile dysfunction
- Alleviates common symptoms of premenstrual syndrome
- Supports symptoms involved with PCOS
- May relieve pain and inflammation from endometriosis
- Alleviates anxiety associated with menopause
7.1 CBD For Premenstrual Syndrome (PMS)
Premenstrual syndrome (PMS) is a prevalent condition experienced by up to 95% of women of reproductive age.
This condition occurs up to a week before the menstrual phase of the woman’s reproductive cycle. Hormonal changes that occur as the body prepares for menstruation result in a series of psychological and physical symptoms.
The effects of PMS are different for everybody and can range in severity from mild to extreme.
Many women are using CBD oils to support PMS symptoms, such as anxiety, muscle cramps, mood changes, pain, insomnia, and more.
The benefits of CBD oil for PMS include:
- Alleviates anxiety
- Supports mood and alleviates symptoms of depression
- Relieves abdominal cramping and pain
- Supports sleep quality
- Resists the formation of acne breakouts
Evidence: CBD & PMS
There aren’t any studies specifically looking at the effects of CBD for PMS, but there are plenty of studies that have shown direct benefits from CBD for the common symptoms associated with the condition (pain, cramping, and mood changes).
During the luteal phase (the phase just before the menstrual phase), dramatic changes in progesterone and estrogen can affect serotonin levels in the brain. A drop in serotonin activity during this phase is thought to be one of the primary causes of the mood changes associated with PMS.
CBD has been shown to alleviate low serotonin activity in the brain [National Academies of Sciences 2017]. This is suggested to be one of the key reasons why CBD is so effective for stabilizing mood during PMS.
7.2 CBD For Polycystic Ovarian Syndrome (PCOS)
Polycystic ovarian syndrome (PCOS) is poorly understood. We still don’t know the underlying cause of this condition, making it hard to both diagnose and treat.
PCOS is more or a metabolic disorder than anything else. It involves a widespread imbalance in female reproductive hormones, male androgens, and insulin.
CBD isn’t a cure for PCOS, but it can help support several of the underlying mechanisms involved with the progression of symptoms.
The benefits of CBD oil for PCOS include:
- Supports optimal insulin levels
- Supports weight loss
- May relieve common side effects of PCOS
Evidence: CBD & PCOS
A large-scale analysis study looked at the results of data obtained from the National Health and Nutrition Examination Survey from 2005 to 2010 to correlate the impact of cannabis on insulin resistance [Penner 2013]. The study found that participants of the survey that used cannabis regularly had 16% lower insulin resistance scores than non-users.
While this particular study looked at the effects of any cannabis product (including marijuana), researchers suggested CBD as one of the key compounds responsible for this insulin-regulating benefit.
7.3 CBD For Endometriosis
Endometriosis is a condition where tissue that grows inside the uterus mistakenly grows outside the uterus. This special tissue (endometrial tissue) is adapted to change in response to female hormones throughout the menstrual cycle.
This tissue itself isn’t harmful on its own, but the problem comes during the menstrual phase when this tissue is triggered by hormone changes to begin shedding.
Endometrial tissue inside the uterus is pushed out of the body through the vaginal cavity. The tissues growing outside the uterus become trapped in the body. This can result in severe pain and inflammation. Over many cycles, it can eventually lead to scar formation on the ovaries, uterus, and fallopian tubes.
CBD is not a cure for endometriosis and will not prevent the growth of endometrial tissue. However, it can offer benefits for the common side effects of the condition.
The benefits of CBD oil for endometriosis include:
- Alleviates inflammatory pain
- Reduces muscle cramping
- Blocks the effects of inflammatory prostaglandins
- Regulates hormone production
Evidence: CBD & Endometriosis
Women diagnosed with endometriosis were asked about their experience using CBD to manage pelvic pain associated with the condition [Reinert 2019]. Of the survey respondents that have tried CBD, 57% reported CBD to be very or moderately effective.
8. Regulates Hormones & Metabolism
The endocannabinoid system is intimately involved with regulating the endocrine system — which involves the hormone-producing organs in the body.
CBD has been shown to support reproductive hormones (covered in more depth in section 7) and metabolic hormones.
When it comes to metabolism, CBD offers several key benefits that make it useful for managing long-term problems involving insulin resistance and weight gain.
This supplement isn’t sufficient on its own, but when combined with other diet and lifestyle changes, it can offer substantial benefit on the overall metabolic system — which includes organs such as the pancreas (the source of insulin), the liver, the digestive system, the kidneys, adipocytes (fat-storage cells), and the brain.
The major benefits of CBD on metabolism include:
- Regulates insulin production
- Reduces appetite to curb cravings and support weight loss
- Protects the liver, kidneys, and pancreas
- Supports the effects of insulin
- Fights chronic inflammation
- May support blood lipid levels
8.1 CBD For Diabetes
Diabetes is a metabolic disorder involving the hormone insulin. This hormone is responsible for moving sugar from the blood to the inside of cells, where it’s converted to energy. If there isn’t enough insulin (type I) or the insulin doesn’t work properly (type II) — it leads to diabetes.
CBD is not a cure for diabetes, but it does offer useful benefits for supporting insulin function, alleviates side effects like pain, and offers protective effects on the organs most affected by diabetes (such as the liver, kidneys, and pancreas).
The benefits of CBD for diabetes include:
- Helps curb appetite & reduce weight
- Protects the liver
- Alleviates neuropathic pain
- Alleviates other side effects of diabetes
- Supports insulin function
- Supports faster wound healing
- Protects the insulin-secreting cells in the pancreas
Evidence: CBD & Diabetes
A study done in 2013 involved 4700 patients with prediabetes (elevated blood sugar that remains below the threshold for diabetes) who were screened to measure the effects of cannabis on insulin sensitivity [Penner 2013]. The study found that people who used cannabis products had an average of 16% lower fasting insulin scores (a marker of lower insulin resistance).
In animal studies, overweight rats given cannabis extracts over long periods had a heavier pancreas than rats in the control group [Levendal 2012]. This study suggested cannabis has a protective effect on the pancreas. A common side effect of high blood sugar levels is damage and destruction of the pancreas — leading to less insulin secretion and a worsening of symptoms as the disease progresses.
CBD also offers benefits in the form of appetite suppression [Matias 2006]. Obesity is a major contributing factor to the progression of type II diabetes. Achieving and maintaining optimal BMI is one of the primary treatment goals for managing this condition.
8.2 CBD For Fatty Liver Disease
There are two forms of fatty liver disease — alcoholic fatty liver disease (FALD) and nonalcoholic fatty liver disease (NAFLD). CBD is a cure for neither, but there is evidence it can help slow the progression of both.
Fatty liver is a serious medical condition that can usually be prevented if changes are made to both diet and lifestyle (taking steps to control weight and sugar intake, quitting alcohol, exercising regularly).
CBD offers supportive benefits by regulating the endocannabinoid system — which is involved with liver function. This compound may slow the progression of the disease for long enough to make the other necessary changes to diet and lifestyle habits.
The benefits of CBD oil for fatty liver disease include:
Evidence: CBD & Fatty Liver Disease
An animal study fed mice a high fat, high-calorie diet for 15 weeks to induce fatty liver disease [Romero-Zerbo 2020]. Half the animals were given daily doses of CBD for two weeks to measure its protective effect. Researchers reported that blood lipid and bodyweight remained comparable in both groups at the end of the study. However, the CBD group had better insulin resistance scores, reduced liver inflammation, reduced fibrosis in the liver, less cell death in the pancreas, and fewer signs of fatty liver disease overall.
Experimental studies have suggested that the primary benefit of CBD for fatty liver disease is the result of CB1 endocannabinoid receptor inhibition [Alswat 2013]. CBD is a modulator of the endocannabinoid receptors, which means it can both increase and decrease receptor activity.
8.3 CBD For Metabolic Syndrome
Metabolic syndrome is a complex disorder involving the way the body stores and uses sugar and fats for energy. This condition is caused by lifestyle factors such as poor diet (high sugar and fat intake) and lack of exercise.
The only effective treatments for this condition are diet and lifestyle changes. High sugar and high-fat foods, increased caloric intake, lack of exercise, and use of liver-toxic substances like alcohol and nicotine all need to be cut out to stop or reverse the progression of metabolic syndrome.
CBD can’t cure or prevent this condition but may offer support for a few of the underlying processes involved with the progression of the disorder.
The primary underlying causes of metabolic syndrome are insulin resistance, obesity, fatty liver disease, and chronic inflammation — all of which CBD has been shown to offer direct benefits.
The benefits of CBD oil for metabolic syndrome include:
- Reduces appetite
- May slow the progression of fatty liver disease
- Improves insulin sensitivity
- Alleviates neuropathic pain
- Protects the insulin-secreting cells in the pancreas
- Reduces inflammatory load
Evidence: CBD & Metabolic Syndrome
A study done in Australia involving nearly 1.5 million patients was used to identify correlations between cannabis use and incidences of metabolic syndrome [Waterreus 2016]. The study found that patients who used cannabis had a significantly lower chance of developing metabolic syndrome than non-users.
More research in the form of clinical trials is needed to understand the benefits of CBD for metabolic syndrome fully.
8.4 CBD For Weight Loss
Achieving and maintaining ideal body weight (based on body mass index or BMI) is one of the best steps you can take to maintain optimal health and wellbeing. While being slightly overweight is unlikely to significantly impact your health, obesity is correlated with a wide range of health conditions long term.
The best way to lose weight, by far, is through diet and exercise. In some cases, you may need to address other underlying factors contributing to weight gain as well — such as thyroid or hormone dysfunction.
CBD offers several benefits that support weight loss but isn’t enough to cut weight on its own. For best results, CBD should be used in combination with other weight loss treatments — such as calorie-restrictive diets, exercise regimens, and quitting alcohol or cigarettes.
The benefits of CBD oil for weight loss include:
- Reduces appetite to curb eating habits
- Alleviates chronic inflammation associated with obesity
- Supports optimal hormone function
- Alleviates digestive disorders & inflammation
- Supports mitochondria function (where sugar & fat is burned for energy)
- May reduce insulin resistance
- Alleviates stress & anxiety
Evidence: CBD & Weight Loss
The research around the weight loss benefits of CBD is limited, but there are a few good correlational studies and animal studies that suggest CBD as a promising candidate for weight loss programs.
Recent animal studies have shown CBD may reduce weight by boosting metabolism and reducing appetite [Koch 2017]. This study found the mechanism of action relied on CBDs interaction with the CB1 and CB2 endocannabinoid receptors — both of which play a role in both fat and sugar metabolism.
The Benefits of CBD For Children: Is it Safe?
CBD is entirely non-psychoactive as long as it’s made from hemp plants instead of marijuana. It’s been proven safe for children, even in very high doses.
Several large clinical trials have already been completed exploring the efficacy and safety of using CBD products with children.
A meta-analysis published in 2018 explored the effects of CBD on 607 patients between the ages of 5 months and 67 years with treatment-resistant epilepsy (average age 13) [Szaflarski 2018]. Researchers reported that CBD was very well tolerated by patients of all ages. The most common side effects reported were fatigue and diarrhea — even in very high doses (up to 10 mg/kg).
There are many reasons why a parent may want to use CBD products with their children. CBD offers all the same benefits for children as it does for adults. Its primary use is to relieve anxiety, manage inflammatory disorders or chronic pain, or support specific health conditions.
The benefits of CBD oil for children include:
- May alleviate symptoms of ADD & ADHD
- May support common side effects of autism spectrum disorder (ASD) — such as anxiety, insomnia, seizures, and mood disorders
- May alleviate symptoms of childhood asthma
- Can help with sleep in agitated children
- May prevent or alleviate nausea & motion sickness
- Useful for certain epileptic disorders (such as Dravet’s syndrome)
- Can help relax the lungs to help with coughing
- Natural anti-inflammatory
- Alleviates anxiety & stress disorders in children
What Are the Side-Effects of CBD?
All health supplements and medications bring the risk of side effects. The severity of these side effects depends on the individual substance.
Compared to other health supplements, CBD has a very low risk of producing side effects. Most people who experience side effects report the reaction to be mild — most commonly involving tiredness or dizziness.
In more severe cases, CBD may cause a noticeable drop in blood pressure, diarrhea, or nausea — though these are very rare.
Side effects become more common with high doses of CBD and when using it alongside other medications, supplements, or alcohol.
The most common side-effects of CBD include:
Key Takeaways: The Benefits of CBD
CBD is a very useful supplement — offering a broad range of benefits across multiple organ systems. It’s used to support neurological function, cardiovascular health, immune function, and much more.
This impressive molecule can offer all these benefits by interacting with a system responsible for regulating different processes around the body — called the endocannabinoid system.
By supporting this system, CBD can affect hormone production, nerve function, inflammation, pain transmission, and more.
The 2022 Definitive Guide to CBD Oil + Benefits Chart
You’ve seen advertisements for anything from CBD bath bombs to CBD toothpaste . Your friends— and even your parents —have been talking about CBD.
Now you’re ready to see what all the buzz is about. Well, you’ve come to the right place.
We put together this ultimate guide to CBD oil to give you all the information you need to launch a CBD-infused lifestyle.
If you want to hop right into our top suggestion at SnackNation, then check out Vitalibis – the first CBD oil that we trust due to their certified organic farming practices.
Browse the topics below to learn the difference between full-spectrum CBD oil and CBD isolate, find out what research says about CBD, and get the tips you need to discover your perfect CBD product.
Everything You Need to Know About CBD Oil
- What is CBD Oil?
- CBD Oil With THC
- CBD Oil Without THC
Taking CBD Oil
- How Long Does it Take for CBD Oil to Work?
- CBD Oil Drug Test
- CBD Oil Uses
- CBD Oil for Pain
- CBD Oil for Anxiety
- CBD Oil for Sleep
CBD Oil For Other Ailments
CBD Product Guide
CBD Vape Oil and CBD Vape Juice
Other CBD Products
CBD Oil Reviews
CBD Terms Glossary:
- CBD (short for cannabidiol): A plant-based compound known for its calming effects. CBD comes from hemp and cannabis plants.
- Cannabis: A type of cannabis plant that contains 0.3% or more of the psychoactive compound, THC (tetrahydrocannabinol).
- Hemp: A type of cannabis plant that contains 0.3% or less of the psychoactive compound, THC (tetrahydrocannabinol).
- THC(short for tetrahydrocannabinol): A plant-based compound known for its psychoactive properties. THC comes from cannabis plants.
- Marijuana: Pieces of dried cannabis plant with high levels of THC (tetrahydrocannabinol).
- Psychoactive: Substances that affect the mind, mental processes, or behavior.
- Cannabinoids: Biologically active chemical compounds found in cannabis plants.
- Endocannabinoid system: A sophisticated molecular signaling system in all vertebrates that, among other things, allows us to feel the effects of cannabinoids.
- Certificates of Analysis (COA): Document that shows all the ways a product meets a list of specifications. Often created by third-party laboratories with no association to the manufacturer of the product, COAs ensure accuracy of marketing claims.
- Measurable: Verifiable. Based on empirical evidence such as numbers and data.
- Anecdotal: Unverifiable. Based on personal reports, observations, and opinions.
The information in this post is meant to be informational. We are not offering medical advice, legal guidance, or product endorsements. This information was not collected or reviewed by medical or legal professionals.
Have You Heard Of The Employee Retention Credit?
What is CBD?
The short answer: CBD is a plant-based compound known for its calming effects.
Your CBD adventures start with one fundamental question: What is CBD?
CBD —or cannabidiol if you like using words with lots of syllables—is, in the most basic terms, a chemical compound. The words “chemical” and “compound” might make you think of synthetic substances created in a laboratory, but guess what? CBD is 100% natural. In fact, it comes from a plant you’ve probably heard of before: the cannabis plant.
Some people freeze when they hear the word “cannabis.” That’s because many people use “cannabis” and “marijuana” synonymously to describe the drug that gets you high.
When we’re talking about cannabis in the context of CBD, we’re just talking about a plant that contains over 400 compounds called cannabinoids. Some cannabinoids, like tetrahydrocannabinol, or THC, are psychoactive; they affect your mental processes. Many cannabinoids, including CBD, are not psychoactive.
What Does CBD Stand For?
The short answer: CBD stands for cannabidiol.
CBD stands for cannabidiol. The term spares us from trying to say and spell cannabidiol over and over again.
The “cannabis” portion of the word indicates the compound’s origin in the cannabis plant. The “diol” portion of the word indicates the two alcohols in the compound. (In this case, alcohol simply describes a molecule made of carbon (C), oxygen (O), and hydrogen (H) atoms—not a tasty adult beverage.)
Most cannabinoids have similar names . This makes it easy for us to tell they share cannabis as their mother plant.
- Cannabidiolic Acid (CBDA)
- Cannabinol (CBN)
- Cannabigerol (CBG)
Does CBD Get You High?
The short answer: No.
Many people react to this statement with a healthy dose of dubiousness. Why not? It comes from the cannabis plant!
CBD alone—when it’s not paired with other compounds in the cannabis plant, such as THC—does not produce the psychoactive (mind-altering) effects we perceive as “getting high.”
Just one of the many compounds found in the cannabis plant, CBD can be isolated from the other compounds to make a product with practically no chance of triggering a high.
However, CBD products often contain some THC, which is psychoactive. Check the labels and certificates of analysis (COA) to find out if your product contains any percentage of THC.
CBD Clinical Trials
The takeaway: Keep an eye out for news of CBD clinical trials that will verify or call into question the promising health benefits many believe CBD provides.
Throughout this post, you’ll learn that many experts withhold their optimism on the benefits of CBD, pointing to a lack of evidence from controlled trials and systematic research. Promising results from CBD clinical trials would give them satisfying evidence.
Clinical trials on CBD have been relatively limited so far, but, as CBD benefit claims multiply and CBD popularity grows, we’ll likely see more trials.
If you want to see some hard data from current and completed clinical trials, then you can browse the United States National Library database of CBD clinical trials.
THC vs CBD
CBD and THC are different compounds. THC is psychoactive; it affects your mental processes (it gets you high). CBD is not psychoactive.
CBD and THC, like siblings, have a lot in common, but they also have many key differences.
Different compounds, or cannabinoids, CBD and THC both come from the same parent plant, but they interact in your body , specifically in your body’s endocannabinoid system, in different ways.
CBD and THC share a molecular structure, but they have a different arrangement of atoms. This simple difference in atomic arrangement explains why the two compounds interact with your endocannabinoid receptors in different ways and why CBD doesn’t get you high while THC does.
How Long Does CBD Stay in Your System?
The short answer: CBD can stay in an average person’s system for up to 5 days. However, the length of time CBD stays in any individual’s system fluctuates depending on a variety of factors, including dosage, CBD form, the person’s weight, and more.
If there’s any chance you might have to take a drug test , then, of course, you’ll wonder how long CBD stays in your system, just in case. (But for the record, if the CBD you took contains no THC or CBN, then you should be fine, even if the CBD is still in your system.)
Studies investigating CBD’s lifespan in the body have found—in general—that the compound can stay in the blood for up to 5 days. Other studies found that CBD might stay in the urine for only 24 hours.
Just as different bodies and different circumstances affect the metabolism of food and alcohol, different circumstances and bodily characteristics affect how a body will absorb, process, and retain CBD.
So what factors are most influential to how long CBD will stay in your system?
- How you take the CBD. (Results will differ depending on whether you ingest, smoke, or vaporize your CBD.)
- Your own individual metabolism.
- What else, including food, is in your system when you take the CBD.
- How much CBD you take and how often.
What Drugs Should Not Be Taken with CBD?
The short answer:
Many drugs could interact with CBD, and it’s important to check with your doctor before you mix CBD with medications, including over-the-counter medications.
In the grand scheme of things, experts have really only scratched the surface of CBD research, experiments, and investigations. That’s why you’ll have a hard time finding a straightforward answer about what drugs you should not mix with CBD.
Experts do know that our bodies use the same set of enzymes to metabolize CBD as we use to metabolize most medications available on the market. That means there’s a chance CBD could interact with a majority of medications.
This doesn’t mean that the interactions would be catastrophic, significant, or even noticeable; it just means there’s a big chance CBD and your medication could interact and alter each other’s intended effects, leading to different outcomes in your body.
It will take years for experts to develop a more straightforward answer to this question. For now, play it safe by talking to your doctor or pharmacist before mixing CBD strains with any medications.
CBD Dosage Calculator
If you’re trying CBD for the first time, then you probably have no idea how much to take.
All the products you find have vastly different concentrations, so it’s hard to even guess what a standard dose might be.
Try to find your ideal CBD dosage by using this crowd-sourced CBD dosage calculator .
You simply plug in some information, and the calculator recommends a dosage. The tool calculates answers based on their pools of self-reported user data.
This is the perfect place to start if you’re new to CBD or if you haven’t achieved the results you were hoping for so far in your CBD adventures.
Everything You Need to Know About CBD Oil
What is CBD Oil?
The short answer:
CBD oil is simply the CBD compound infused into a carrier oil.
So we know CBD is technically a compound, a non-psychoactive cannabinoid that reacts with receptors in our bodies to produce a calming effect.
Now it’s time to get into more practical questions. How do you actually get CBD into your body?
Oil is one of the most popular vessels for CBD.
CBD oil is essentially just the CBD compound infused into a carrier oil. After that infusion, the oil will have a concentration of CBD . There’s no standard concentration of CBD across CBD oils, so the potency of these products varies.
CBD oil products mimic the naturally oily plant material they’re extracted from.
Have you ever wondered why so many CBD products are CBD oils?
The CBD-rich parts of the cannabis plant are naturally resinous and oily. So when we extract the CBD from these bits, what we get is already thick and oily. It’s primed for infusions into other carrier oils.
So when you enjoy a CBD oil, you’re enjoying CBD close to its natural state.
To dive even deeper, the CBD we extract to create oils and other products come from trichomes. Some experts call trichomes “ plant hair ,” because of their growth structure and their ability to retain metabolites. (Even the word “trichomes” comes from the Greek word for “hair.”)
Naturally resinous, the CBD solvent we can extract from trichomes will vary in CBD potency, depending on the CBD present in the trichomes and also the method used to extract the CBD from the trichomes.
CBD Oil Effects
A wide range of users reports a wide range of effects when taking CBD.
So we’ve established that CBD does not get you high as its cousin, THC, does. So what does CBD do? What are the main potential effects that attract people to this trendy compound?
Before we dive in, let’s group the types of CBD benefits into two categories:
Measurable effects: These outcomes have been studied, quantified, and corroborated by multiple controlled studies and trials. These effects involve measurable factors, such as the number of seizures or blood pressure readings.
- Some measurable effects of CBD include:
- Decreased risk of heart disease
- Seizure management
Anecdotal effects: These outcomes have been reported by CBD users, but they don’t include a measurable component or they simply can’t be measured. For example, a reduction of pain is an anecdotal benefit because we have no universally accepted measurement for pain, and pain is subjective—it lives in the “eye of the beholder” so to speak.
- Some anecdotal effects of CBD include:
- Decreased anxiety.
- Mitigated addiction withdrawal symptoms
- Lessened pain
CBD Oil Benefits
CBD’s reported benefits hold promise for a variety of health issues.
People who’ve tried CBD have reported a wide range of benefits. While many effects and benefits could be considered subjective, these benefits also come along with anecdotal evidence that could be extremely compelling for anyone looking to achieve similar benefits.
- Pain management. Studies showed rats on CBD had decreased activity in brain regions associated with pain.
- Anxiety and depression reduction . One study showed that CBD can reduce anxiety in humans preparing to speak publicly. Animal studies demonstrated effects similar to antidepressants.
- Chemotherapy side effect management. CBD reduces chemotherapy-induced nausea.
- Skin clearing. A laboratory test-tube study showed that CBD might help block the production of excess skin oils and the inflammatory response that leads to acne.
- Seizure management. CBD helps reduce epileptic seizures. Heart health. Some research subjects saw a decrease in blood pressure when taking CBD, and CBD appeared to be able to reduce inflammation and cell death in patients who had already succumbed to heart disease.
What is CBD Oil Good For?
The short answer:
Seizure reduction. CBD is potentially good for a number of things, but seizure reduction is the most research-backed CBD benefit.
People anecdotally report a variety of CBD benefits . However, when it comes to benefits that most experts agree has enough measurable evidence (from systematic trials and research), epileptic seizure reduction takes the cake.
Even the U.S. Food and Drug Administration (FDA) found the evidence for CBD’s seizure reducing abilities compelling enough to pursue.
The FDA’s expert panels found enough evidence to approve a CBD-based treatment for epilepsy . This particular approval made history as the first FDA acceptance of a drug made from cannabis.
What about the other purported benefits of CBD?
While many people report a range of other benefits—and there is some evidence to back them up—experts want multiple trials and multiple peer-reviewed studies to verify any claim before they start making any conclusive statements that could give patients false hope.
CBD Benefits Chart
If your head is spinning from hearing about one CBD benefit here and another there, then you need something that can give you a quick view of the full range of anecdotally reported CBD benefits. You need a CBD benefits chart.
This comprehensive chart from The Physicians’ Choice bullets out a complete list of potential CBD benefits.
As an added bonus, the chart also lists the benefits of other cannabinoids, including THC, CBN, and CBDA.
Here are some potential CBD benefit highlights from the chart:
- Antibacterial properties
- Cancer-fighting capabilities
- Pain and anxiety relief
- Seizure reduction
- Bone-boosting capabilities
- Neuron shielding abilities
- Psoriasis treatment potential
Is CBD Oil Legal?
The short answer:
CBD from industrialized hemp is federally legal. However, for your practical purposes, you need to know how hemp—and cannabis for that matter—is regulated in your state .
CBD from industrialized hemp is federally legal , but if manufacturers make claims of “therapeutic benefits,” then the product could be regulated, meaning a manufacturer could be selling and marketing legal CBD in a way that is unlawful .
Find additional information about cannabis and the legal use of CBD here.
If you’re a real policy wonk, then you might what to peruse the full texts of these relevant documents:
The Hemp Farming Act
To make things more complicated, the source of CBD could make a difference when it comes down to regulations.
- Industrialized hemp is federally legal
- Cannabis is federally illegal
- CBD can come from either hemp plants or cannabis plants
- So if you live in a state that has legalized recreational marijuana, then you’re likely in the clear no matter what.
- However, if you live in a state that does not allow marijuana, and you happen to buy CBD sourced from cannabis instead of hemp, then you could run into trouble.
The moral of the story is: know your state’s hemp and cannabis regulations. Never assume that your ability to purchase a product means it’s legal.
CBD Oil Side Effects
The takeaway: Based on current reports, CBD users could experience dry mouth, lightheadedness, drowsiness, nausea, or anxiety.
HugsCBD reminds us that CBD, a young product from a young industry, has enjoyed fewer tests and research studies than nearly any prescription or over-the-counter medication. (After all, those laundry lists of possible side-effects that make you panic and give you a headache come from years of research and observation!)
Here are some of the CBD side effects that have been reported so far. These are all side effects some people have experienced. There’s no guarantee you will feel any of these effects or that you won’t feel effects that aren’t on this list.
Common short-term side effects:
- Dry mouth
Common long-term effects:
CBD will need to be on the market for several years before we have a comprehensive list of long-term consequences.
- Dental issues . This relates to the short-term side effects of dry mouth. Moisture protects your teeth and gums, so a dry mouth leaves people more susceptible to cavities and gum problems.
- Increased liver enzymes . Whether this effect grows ultimately into a net positive or a net negative remains to be seen.
CBD Oil Research
When it comes to what the research indicates definitively, or nearly definitively, on CBD, experts say, “the jury is still out.”
The headline of this Northwestern Medicine post sums up the research conducted to date on CBD perfectly: “Promising, But Not Yet Proven.”
The post includes expert opinions and commentary from researchers and medical practitioners, the people in the front lines who observe CBD’s effects in laboratories and on patients. The experts aren’t sold on CBD’s benefits, saying that in most cases, “the jury is still out.”
Experts agree that CBD’s use against seizures has satisfactory evidence, but they want consumers to remember that the general idea that CBD is “broadly beneficial” is a bit of a myth. They don’t want to call anything a cure-all until more evidence supports the claim.
So what can we get excited about now? Get excited about the future, but as you read about health claims (which you’ll probably see more and more of as CBD grows more popular), look for the evidence before you make any assumptions.
CBD Oil vs Hemp Oil
If consuming CBD is your ultimate goal, then read the labels of all the products you purchase.
Products called “CBD oil” and products called “hemp oil” might be nearly the same when it comes to CBD content, but they can also be radically different depending on their plant components, their plant sources, and the ways they were produced.
Consumers can expect to be confused by terms like “CBD,” “hemp,” and “marijuana.” All these terms have multiple meanings and can be used in popular but incorrect ways, which only adds to the confusion.
The root of the matter lies in the plant sources. CBD is found in both hemp plants and cannabis plants. Hemp and cannabis are like identical twins in the plant world : they look and smell almost exactly the same, so they’re hard for people to distinguish.
As the experts at Phys Org put it, “ Cannabis plants with 0.3 percent or less of THC are hemp. Cannabis plants with more than 0.3 percent THC are marijuana.”
What does this mean for CBD products? Here’s a little cheat sheet based on information from Medical News Today :
- CBD oil = hemp or cannabis stalks, leaves, and flowers. CBD oil will always include CBD. (Of course!)
- Hemp oil or hemp seed oil = hemp or cannabis seeds. These products may or may not include CBD.
CBD Oil With THC
In locations where recreational marijuana is legal, consumers can enjoy CBD oil and products that contain some percentage of THC if they want a mild high without some of the negative effects of THC.
Leafly has the necessary details for anyone hoping to blend their CBD with some THC.
The basic breakdowns of CBD and THC combinations can be summarized in three basic “configurations.”
- High THC and low CBD (Leafly says products that are 10-30% THC and contain only a little CBD fall into this category.)
- Balanced amounts of THC and CBD (Leafly says products that are 5-15% of both THC and CBD fall into this category.)
- High CBD and low THC (Leafly says products that are 5-20% CBD and 5% or less of THC fall into this category.)
High CBD products work best for consumers who don’t want to get the euphoric high THC provides or for consumers who have a particular sensitivity to THC.
CBD Oil Without THC
When you’re browsing for CBD oil, check to see if the product has a third-party lab report and certificate of analysis (COA) that verifies the product contains no THC.
CBD oil with no detectable THC will provide only the purported calming effects of CBD without any of the “high” that comes along with THC.
These products work well for people who can’t consume any THC due to their jobs.
CBDoilusers.com has pre-screened some THC-free products (including oils, vape juices, and gummies) to save you research time. Their recommended brands include:
Taking CBD Oil
How to Take CBD Oil
The short answer:
It depends on what you want the CBD to do.
Foria has a complete set of suggestions for determining how to take CBD to achieve the effect you want. Here are some prompts based on their post to help you figure out how you should take CBD:
- What do you want to get out of your CBD? (Pain relief, stress relief, or creativity?)
- How fast do you need the CBD to work?
- Foria advises using inhaled CBD products (like vaporizers) to get quick relief and oral products to get relief throughout the day.
- As you experiment with CBD, pay attention to the effects and document your dosages. If you’re new, start with a low dose and slowly add more.
- The CBD percentages listed on labels don’t translate to literal absorption for every person. The percentage of CBD in a product is how much you might absorb if your body processes the product perfectly, which it probably won’t.
- Check all the instructions on the label of your product. Many of them include tips for optimal absorption.
CBD Oil Dosage
The United States Food and Drug Administration has not yet established dosage recommendations on CBD.
If you’re new to CBD, then your best bet is to ask your doctor where to start and experiment from there.
CBD affects different people differently, kind of like how caffeine affects people differently.
If you drink coffee, then you’ve probably noticed that caffeine impacts you differently than it impacts your friends and co-workers. Maybe your hand starts shaking halfway through your first cup while your friend is still yawning through her second cup.
And it’s not just your baseline chemical makeup and bodyweight that can impact how CBD affects you. Your reaction can change from day to day depending on what kind of food you’ve eaten or how much sleep you’ve had.
Don’t worry—with some experimentation and observation, you’ll soon know how CBD affects you.
Healthline recommends asking your doctor where to start. If that’s not an option, then you can go with one of the most popular starting doses: 20 – 40 mg per day.
Scale up or down in increments of 5 mg per day until you achieve the desired effect. Keep a diary or log so you remember how much CBD you took and how it affected you.
This crowd-sourced CBD dosage calculator can also help you do your own research.
How Long Does It Take for CBD Oil to Work?
The short answer:
It depends on your body chemistry, how much you take, what form you take it in, where it was sourced, and more.
An expert quoted in this Well + Good article puts it perfectly when she says CBD “isn’t one-size-fits-all.”
When you ask how long it takes CBD to work, what you’re really asking is: How long will it take my body to absorb the CBD?
Absorption and effects should occur simultaneously.
Here are the main factors that affect your absorption:
- The form of your CBD.CBD edibles will likely affect you more slowly as your body has to break down some food to get to the CBD. CBD tinctures will likely be quicker to impact you.
- The quality of your CBD. Full-spectrum CBD oils retain the full range of compounds that provide blissful CBD feelings. You should also check products for third-party lab reports and certificates of analysis (COA) that verify exactly what you’re getting in your product.
- Dosage. The more CBD you consume, the faster you’ll feel the effects.
- Your body weight and body chemistry. Be mindful as you try CBD and start figuring out how fast it usually works for you.
CBD Oil Drug Test
CBD alone will not trigger a false-positive drug test for THC.
Researchers did a test to confirm that CBD doesn’t show up on some of the most popular screening tests used to detect THC.
However, cannabinol (CBN) did trigger a positive test, and of course, products with some THC triggered a positive test as well.
CBD products do not yet have to pass federal regulations before they go on sale, but consumers can rely on third-party lab tests to make sure they’re getting pure CBD without any CBN or THC.
CBD users can also rest assured that most positive drug tests trigger confirmation screenings, especially if someone disputes a false positive.
These more complex confirmation tests can see the difference between CBN and CBD, and will only pose problems if the CBD product also contained THC.
CBD Oil Drug Interactions
Always, always check with your doctor about potential CBD and drug interactions.
We know too little about CBD so far for anyone to be sure how it might react with the vast number of prescription and over-the-counter drugs available today.
Your doctor or your pharmacist will best know how CBD might interact with the other drugs you’re taking.
If you want to do your independent research, then check out the Drugs.com comprehensive list of drugs known to interact with cannabis.
Drugs have shown to have major or clinically significant reactions include:
So while the information we have now is currently sparse, the list will continue to grow as we do more research.
CBD Oil Uses
Research and trials tell us that CBD, when used to treat seizures, in the form of a prescription drug, Epidiolex, is safe and effective.
Most experts endorse the usage of CBD to combat epileptic seizures. There’s even an FDA-approved drug for this use.)
For all other usages and benefits, medical practitioners are waiting for more research before they say anything conclusive.
That said, many people are already using CBD in a variety of forms for a variety of ailments.
- Forms of CBD use include oil, vapor, massage oils, topical lotions and patches, edibles, capsules, and more.
- Reasons cited for CBD use include pain management, stress reduction, sleep improvement, and more.
CBD Oil for Pain
What we know so far suggests CBD may decrease feelings of pain, but we still have a lot left to learn.
While experts caution that we know too little about CBD so far to make absolute claims, they do point out strong evidence supporting the claim that CBD might be used in the future to manage chronic pain.
For example, one review of existing literature examined multiple trials and studies and found that CBD can treat chronic pain.
On top of that, a separate study also found CBD to be effective for treating chronic pain and reducing inflammation.
Subjects didn’t seem to need a higher dosage of CBD as time passed. This contrasts to other painkillers that people eventually build a tolerance to, leading to increased dosages and dangerous addictions.
So if CBD turns out to be effective for pain management, it could help fight the opioid epidemic, but at present, those hopes are merely conjecture.
CBD Oil for Anxiety
Research has shown that a CBD stick can achieve a measurable reduction in anxiety.
In some studies , CBD lessened the behavioral signs of anxiety, which include avoidance, mood swings, and jumpiness.
Other studies show that CBD lessened the physical signs of anxiety, which include sweaty palms, dizziness, racing heart, and chest pain.
These studies show promise for CBD’s use in a range of anxiety disorders, including generalized anxiety disorder (GAD), social anxiety disorder (SAD), and post-traumatic stress disorder (PTSD).
Experts hope CBD may be used alone to treat anxiety disorders or to enhance the benefits of other traditional therapies and medications.
CBD Oil for Sleep
Study evidence and personal reports suggest that CBD may help people fall asleep and get more sleep.
According to the experts quoted in this HuffPost article , CBD’s apparent ability to aid sleep correlates with its ability to decrease anxiety and calm people down.
Scientifically speaking, CBD achieves these effects by interacting with two receptors in your brain:
- GABA: Promotes relaxation and cracks down on overactive brains
- Serotonin: Regulates mood and anxiety
Both of these anxiety-inhibiting effects can open doors to dreamland if the subject’s insomnia stems from anxiety, worrying, and restlessness.
People who’ve had success with CBD and sleep report drifting calmly to sleep and waking up without the grogginess sometimes associated with other sleep aids.
CBD for Pets
Currently limited evidence suggests CBD is safe for pets.
Cnet got the CBD-pet scoop from veterinarian and CBD expert Stephanie McGrath.
As CBD pet products grew more and more trendy over the past few years, Stephanie found herself fielding lots of questions. Unfortunately, she didn’t have answers, and she couldn’t find answers in any existing literature. So she decided to find answers by doing her own research.
Here are some of the most interesting things she found out:
- CBD oil outperformed edibles and creams when it came to achieving the highest (and longest-lasting) concentration of CBD in the blood.
- Current evidence suggests CBD is safe for dogs.
- Stay in the clear by selecting products that come with a certificate of analysis (COA) from a third-party laboratory.
- Keep your eyes open for research updates.
CBD Oil for Dogs
When trying CBD on your pup, talk to your own personal veterinarian, shop smart, and watch for side effects.
AKC’s Chief Veterinary Officer has all the details concerned dog parents need to know before giving their pups CBD.
No formal, systematic studies have been conducted for the effects of CBD on dogs, but experts guess that CBD will have similar effects on dogs as it does on humans.
In fact, the list of possible benefits for dogs are almost identical to the list of possible benefits for humans:
And the list of possible side effects are also in line with what we’ve seen in humans:
- Lower blood pressure
- Dry mouth
When shopping for dog CBD, this vet recommends:
- Checking third-party lab reports for quality and contamination alerts
- Finding organic products made without pesticides or solvents
- Favoring liquid products to achieve the best effects
CBD Oil for Cats
What we know about CBD oil for cats is almost identical to what we know about CBD for dogs.
When trying CBD on your kitty, talk to your own personal veterinarian, shop smart, and watch for side effects.
No in-depth studies have been conducted to formally evaluate the effects CBD has on cats or to determine CBD’s safety for cats
Experts have also not seen anything to suggest CBD is unsafe for cats, and most experts generally recognize CBD as safe for cats.
Pet owners should not let their guards down about all cannabis products. Cannabis plants have been shown to be toxic to cats.
The potential benefits are, again, similar to the potential benefits for humans:
When shopping for cat CBD be sure to:
- Check third-party lab reports for quality and contamination alerts
- Find organic products without pesticides or solvents
- Favor liquid products to achieve the best effects
CBD Oil For Other Ailments
CBD Oil for Migraines
CBD may help reduce migraine pain, but more research is needed, and it’s important to consult your doctor before pursuing a treatment regimen.
If you choose to try CBD to decrease your migraine pain, then be sure you’re getting the pure stuff.
One doctor who happens to be an expert on headaches says CBD could make a good migraine treatment because it works locally and doesn’t lead to intoxication.
As is the case with CBD and many other ailments, the studies on CBD and migraines are so limited, most experts decline to make any official recommendations.
This headache expert also suggests checking the products you’re browsing for purity. You want CBD with no THC or contaminants. So diligently check the lab reports and certificate of analysis (COA) and opt for brands you trust.
- Shop CBD oils [Jump to most potent CBD section]
CBD Oil for Depression
It’s possible that CBD may help with feelings of depression, but scientists need to conduct more controlled trials before we can truly say there is sufficient evidence to make that claim.
While a few studies have generated compelling support for CBD’s potential to treat some ailments, depression is not one of them.
Experts have not ruled out the idea that CBD might be used to treat depression, but they don’t yet have enough evidence to get truly excited.
The good news is that they’re looking into it. The growing popularity of CBD has inspired research and clinical trials around the globe. With luck, we’ll have more solid answers soon.
- Shop CBD oils [Jump to most potent CBD section]
CBD Oil for Cancer
Evidence and clinical trials suggest that cannabinoids may mitigate cancer-related side effects.
Good news! Even the experts at the National Institutes of Health believe they have enough evidence to say that cannabinoids may mitigate cancer-related side effects.
This evidence covers cannabinoids in general, not CBD specifically, and it certainly doesn’t include the kind of CBD oil you might buy at the store. In fact, CBD alone may inhibit some of the enzymes that metabolize anticancer therapies and actually decrease their effectiveness.
The evidence does cover the cannabinoids dronabinol and nabilone. These compounds have been found effective at decreasing nausea and vomiting induced by chemotherapy and have even been approved by the FDA for this purpose.
- Shop CBD good [Jump to CBD food section]
CBD Oil for ADHD
Only anecdotal claims, and no scientific evidence, suggest CBD may be used to treat the symptoms of Attention Deficit Hyperactivity Disorder (ADHD) / Attention Deficit Disorder (ADD).
Some people have reported that CBD helps their ADHD or ADD, but physicians and researchers say there is no scientific evidence to support a positive correlation between CBD and ADHD or ADD.
In CBD Oil for ADHD? New Research On This Popular Natural Treatment , ADDitude quoted a variety of experts. Here’s the gist of what they have to say:
- Zero evidence (published data or clinical trial results) provide evidence that CBD should be used to treat ADHD.
- Zero evidence suggests it would even be safe to use CBD to treat ADHD.
- No literature suggests what CBD dosage would even be appropriate for treating ADHD.
- While many people say CBD has helped with their ADHD, hearsay has never been a sound basis for medical recommendations.
- Shop CBD gum [Jump to CBD gum section]
CBD Oil for Seizures
Experts have studied CBD’s impact on seizures for years, and a diverse portfolio of evidence—including laboratory reports, subject reports, and clinical trials—demonstrate that CBD can control seizures.
Of all the ailments people hope CBD might help, seizures are one of the most studied. Even better, the evidence gleaned from these studies is compelling.
Most experts agree that the evidence is strong enough to say CBD can help control seizures of patients with Dravet syndrome and Lennox-Gastaut syndrome (LGS).
The U.S. Food and Drug Administration (FDA) has even approved an oral CBD solution EPIDIOLEX ® for the treatment of seizures.
- Shop CBD capsules [Jump to CBD capsules section]
CBD Oil for Diabetes
Some studies suggest CBD may benefit people with diabetes, specifically by targeting the inflammation associated with diabetes.
Experts hope CBD may help pre-diabetes patients because of the compound’s anti-inflammatory effects, which have been demonstrated in studies of rats.
Inflammation, they explain, often co-manifests with insulin resistance, which can progress into type 2 diabetes. So CBD’s anti-inflammatory effects might be able to halt or slow the progression toward diabetes.
There’s also evidence that CBD when used with other compounds, might decrease blood sugar and insulin resistance in patients who have already progressed to diabetes. So diabetic patients might be able to take CBD to reduce the symptoms of their disorder.
- Shop CBD capsules [Jump to CBD capsules section]
CBD Oil for Autism Spectrum Disorder
Studies of children with autism spectrum disorder show encouraging, but not conclusive, evidence that CBD might alleviate symptoms.
CBD could alleviate the symptoms and effects of autism spectrum disorder.
A few encouraging studies , all focused on children, suggest CBD might alleviate the following autism spectrum disorder symptoms:
- Self-injurious behavior
In addition to alleviating symptoms, CBD may have also helped the studied children communicate and sleep better.
Better yet, the researchers only observed a few negative side-effects, including sleepiness and appetite changes.
While more research needs to be done before we can get truly excited, we can definitely call the observations made so far “encouraging.”
- Shop CBD gummies [Jump to CBD gummies section]
CBD Oil for Weight Loss
Some evidence suggests CBD might help with weight loss, but we need to do more research.
This Medical News Today article covers the evidence we do have to support that CBD may help weight loss. Here are some of the key things we know so far about this correlation:
- CBD may encourage molecules in the body to block off receptors associated with appetite, receptors that obese people typically have more of.
- CBD may help your body convert the most dangerous fat cells into healthier fat cells.
- CBD might help your body burn fat.
All this evidence comes from limited studies or user-reports, so it’s definitely not time to call CBD a weight-loss miracle cure. CBD will affect everyone differently; some people find that it makes them hungrier.
- Shop CBD supplements [Jump to CBD supplements section]
CBD for Inflammation
Inflammation could be the second most studied CBD benefit, coming in behind seizures. And guess what? The evidence we have so far suggests CBD does reduce inflammation.
According to one study published in Future Medical Chemistry , the anti-inflammatory effects of CBD have been observed both in test tubes and in living subjects. All results suggest CBD has the ability to regulate the immune system and ultimately reduce the body’s inflammatory response to foreign invaders.
CBD has been shown to inhibit different inflammatory pathways in different diseases, including those associated with autoimmune disorders:
- Multiple sclerosis
- Rheumatoid arthritis
As chronic inflammation is associated with the development of some cancers, CBD’s anti-inflammatory effects lead researchers to believe the compound could help slow down tumor growth.
- Shop CBD supplements [Jump to CBD supplements section]
CBD Dosage for Inflammation
As the FDA does not regulate the sale of CBD, experts have recognized the need to conduct controlled trials that may lead to standardized dosage recommendations.
Studies on CBD dosage produce results that are as varied as individual study subjects. Experts can only hope to isolate trends they may build on to get to standardized recommendations.
Current studies suggest transmucosal dosage forms might achieve the best CBD effects. These dosage forms include any administration where the drug is delivered through a mucous membrane. These forms include:
- Nasal sprays
- Eye drops
- Below-the-tongue tinctures
These dosage forms prove most effective as they avoid the absorption limitations that spring up when users must metabolize something to absorb their CBD.
Dosage delivery via nanotechnology shows promise for future applications.
CBD Oil for Arthritis
There’s promising, but not conclusive, evidence that CBD can alleviate the pain of arthritis.
CBD’s theoretical potential for arthritis goes back to its anti-inflammatory properties.
Rheumatoid arthritis patients experience a lot of inflammation as their immune system essentially attacks the body.
If CBD can regulate the immune system and limit the inflammatory response, then patients who use CBD may feel less pain in their joints.
While no scientific evidence has shown these effects will actually happen, the basis for optimism is solid.
One trial did show that a combination of CBD and THC in an oral spray relieved arthritis pain, but it’s hard to say which compound achieved which effects.
- Shop CBD oils [Jump to most potent CBD section]
CBD Oil for Fibromyalgia
While little evidence currently supports that CBD may benefit fibromyalgia patients, there are a few compelling reasons to get excited about the possibilities.
So in the face of little scientific evidence, why do some people feel optimistic that CBD can make a viable fibromyalgia treatment ?
Here are some reasons to hope:
- CBD’s anti-inflammatory effects could reduce the pain of fibromyalgia.
- CBD might inhibit the activity of brain cells that lead to sensitivity in the central nervous system and ultimately pain.
- CBD could help with migraines and irritable bowel syndrome often associated with fibromyalgia.
- Many people with fibromyalgia have reported they believe CBD relieved their symptoms.
- Shop CBD oils [Jump to most potent CBD section]
CBD Product Guide
Best CBD Oil
Not all CBD oils are created equally. Smart shopping strategies and a list of trusted brands will help you get the best possible product.
We used the information in this Healthy Moms Healthy Babies (HMHB) post to pull out tips for finding the best of the best CBD oil.
- Check hemp sources and favor locally sourced brands with lab reports.
- Hemp absorbs more from the soil than many other crops. So if there are contaminants or metals in your hemp’s soil, then you could be consuming dangerous substances along with your CBD product.
Here are some of the brands HMHB has vetted for hemp sources, purity, and overall quality:
Pure CBD Oil
Pure CBD oil contains no additives or chemicals.
What is pure CBD oil, you ask? It’s CBD oil without any additives or chemicals or other ingredients that could affect the delivery of CBD into your body.
How do you know if you’re getting truly pure CBD oil? You guessed it! You check the third-party lab report and certificate of analysis (COA) that come along with your product. If the product doesn’t include this, then it’s probably not a good sign for the CBD’s purity.
Check out this CBDfx guide to reading lab reports to start analyzing your products like a professional.
Full-Spectrum CBD Oil
Full-spectrum CBD oils will include the full spectrum of cannabinoids available in cannabis plants. People often compare full-spectrum oils with CBD isolate, which as the name suggests, contains CBD isolated from other cannabinoids.
Since CBD oil includes the full spectrum of cannabinoids, it can produce what experts call an “entourage effect,” where multiple compounds work together to create more intense and possibly more beneficial effects than each compound could have individually.
According to the Street , benefits of full-spectrum CBD oil include:
- It has longer-lasting effects
- It’s usually natural, without pesticides or chemicals
- It’s usually more potent, as it includes a full range of cannabinoids
Organic CBD Oil
Organic in terms of CBD oil means the same thing it means in terms of other crops. To qualify as organic , the product must not have been grown or produced with:
- Genetically modified organisms (GMOs)
- Synthetic fertilizers
- Sewage sludge
- Ionizing radiation
Organic CBD oils are especially popular with people hoping to get creative in the kitchen with their CBD .
According to Plant People , many consumers choose organic CBD oil to:
- Avoid pesticides, which could trigger allergies and may be bad for the environment
- Avoid potentially toxic chemicals and additives
Organic CBD oils accommodate users who typically purchase organic products. Why should their CBD be any different?
Most Potent CBD Oil
The most potent CBD oils, in terms of price per milligram (mg) of CBD, cost about $0.04 per mg.
According to Herbonaut, CBD is more potent when taken together with other hemp-derived compounds. We pulled out the most potent CBD oils per price from some of Rave Review’s picks for the best CBD oils.
$0.04 per milligram CBD oils:
$0.05 per milligram CBD oils:
$0.07 per milligram CBD oils:
$0.08 per milligram CBD oils:
$0.09 per milligram CBD oils:
$0.10 per milligram CBD oils:
Where to Buy CBD Oil
The websites of trusted brands may be the best places to find CBD oil. On these websites, you can read third-party lab reports and all the key product details in the privacy of your own home.
Online shopping for CBD makes doing your research easy!
Get started on the CBD product websites featured on Huffpost’s list of best CBD products of 2019. These brands offer a range of products and forms of CBD.
CBD Oil Prices
CBD oil prices range from alarmingly low to incredibly high. Experts recommend looking at the following factors to determine if you’re paying a fair price:
- Farming practices
- Labor breakdowns
- Marketing, including websites, packaging, and labels
- Testing, preferably completed by a third-party laboratory
- Potency, or CBD per dollar
- Brand’s shipping and distribution footprint
Here’s more information on each of the factors you should consider when deciding how much to pay for CBD:
Remember that creating a quality product can be expensive, so don’t always opt for the most budget-friendly product. It could be less of a bargain if you’re not getting the CBD purity you want.
- Farming practices. High-quality products grown locally and organically will likely cost more than some imported products.
- Marketing, including websites, packaging, and labels. Especially compare these factors to farming and testing practices. Is the company sinking all its money into fancy packaging and neglecting to pay for organic farming techniques and proper testing?
- Testing, preferably completed by a third-party laboratory. Certificates of analysis from these labs are crucial to determining CBD quality, and laboratories don’t typically test for free.
- Potency, or CBD per dollar
- Brand’s shipping and distribution footprint . A high-quality product that only ships locally may be able to charge less than a product of similar quality that has a wider shipping range.
Here’s a selection of the most-loved CBD gummies out there:
By the time you drink your CBD water, it may have already lost its CBD content, especially if it comes in a clear bottle.
According to this Forbes post, low levels of CBD are usually rendered ineffective and destabilized when exposed to light. As CBD water typically comes in clear bottles that receive a lot of light exposure, the CBD it contains may have been reduced to nearly nothing by the time you purchase it or maybe by the time it reaches the store.
A CBD water sold in dark, opaque bottles may be legit. See if the product description explains how the water was created and packaged to maintain CBD integrity.
CBD candy is growing in popularity because it’s a discreet and incredibly enjoyable way to consume CBD.
PureKana , who makes their own CBD candies, touts the following advantages of CBD candy:
- Candy’s sweet flavors mask the sometimes disagreeable flavor of CBD oil.
- Candy is discreet; you can easily pop some in your mouth without revealing that you’re taking anything other than sugar.
- Candy is easy. You just eat it. You don’t have to worry about holding a product under your tongue for a specified amount of time.
- Candy is easy to tote around with you everywhere.
CBD syrup makes a mild, flavorful alternative to CBD oil.
Never tried CBD syrup? No problem! It’s easy to add to water, beverages, teas, fruit, and anything else you want to put a CBD drizzle on. Plus, CBD syrups taste amazing!
CBD syrup is more of a culinary product than CBD oil. The syrups come infused with CBD and usually have their own unique flavor profile that might be as attractive to you as the CBD content.
A versatile CBD product, CBD syrups enable a lot of culinary experimentation. Some people have made delightful pancakes with CBD syrup, crafted flavorful cocktails, and concocted frozen CBD pops.
If CBD syrup sounds like something you might be interested in, then check out CBDBreaker’s roundup of the best CBD syrups.
Chocolate lovers might find happiness in CBD chocolates.
If you like chocolate alone, then you’ll love the euphoric combination of CBD and chocolate.
Chocolate by itself has been known to make people feel euphoric. CBD alone makes some people feel happy and relaxed. Combine chocolate and CBD for a delicious treat that comes along with a dose of bliss. Talk about a satisfying dessert!
CBD chocolates accommodate a range of chocolate lovers, from those who love the darkest of the dark to those who like novelty flavors, like peanut butter and jelly.
The foodies at BonAppetit have a list of their CBD chocolate picks if you’re interested in trying a rich CBD dessert.
It may be counterintuitive to think CBD chewing gum could be effective since you don’t swallow the gum, but if the product is manufactured correctly, it can be more effective than some products you consume .
In CBD Chewing Gum: Practical or Total Gimmick? , the experts at Marijuana Break explain how CBD gum could be more effective than edibles.
Any CBD product you consume has to move through your digestive system before it hits your bloodstream. (This is when you’ll feel the effects of the CBD.)
Your body will metabolize a bit of the CBD as it makes its way through your system. You will not absorb or feel the effects of the metabolized portion; you’ll only feel the effects of the CBD that makes it to your bloodstream.
If you take your time in swallowing your saliva as you chew, then the CBD will get to your bloodstream through the sublingual (below-the-tongue) pathway, and you’ll feel its effects more powerfully.
CBD honey makes another sweet alternative to CBD oils.
Honey alone, especially raw, organic honey, provides a wealth of health benefits thanks to its natural enzymes and antioxidants.
Combining honey with CBD might be a healthy, bliss-inducing way to consume the compound.
Here are some reasons, according to Popsugar , that more people are turning to CBD honey to get a CBD fix.
- It’s delicious. Almost no strange flavors from CBD oil can cut through the sweetness of honey.
- It’s versatile. You can add it to hot beverages, eat it with food, enjoy it by the spoonful, and more. Basically, you can consume CBD honey in all the same ways you consume regular honey.
- It’s a good alternative to refined sugars, and the CBD is an added benefit.
If you want to feel any CBD effects with your CBD food, then be sure to check the dosage.
One Atlantic contributor explains that it’s hard to get a CBD buzz from food because many of the products just don’t contain enough CBD.
CBD is trendy, and production is thriving. However, some manufacturers add just enough CBD to their products so they can call them CBD products, but the items contain as little as 2 mg of CBD, which is probably not enough CBD to produce any effects.
So read the labels, and if you really want to get the benefits from CBD, then maybe try a different type of product.
CBD Vape Oil and CBD Vape Juice
Vape oil and vape juice differ in a few key ways . Vape oils usually have a viscosity similar to a culinary oil. Vape juices will usually be much more liquidy than vape oils.
Each product should only be used in an appropriately designed vaporizer.
- Vape oils may be used with oil vaporizers. These vaporizers container metal plates designed to heat the oil.
- Vape juices may be used with e-liquid vaporizers. These vaporizers have coils and wicks, but no plates.
CBD Vape Juice
Know what you’re looking for when shopping for vape juice. In the absence of federal regulations, it’s up to consumers to set their own standards and hold brands to them.
The experts at Leafly have some advice for consumers to take into account when shopping for CBD vape juice. Here’s the quick take on what you should favor when vape shopping:
- Oils and juices that appear the same throughout, without separation or color mixing
- Clear oils and juices
- Oils and juices that come along with lab test results
- Oils and juices that include CBD from local, organic, and responsible sources
CBD Vape Oil
Many aspects of CBD vaping aren’t intuitive. Do your research to make sure you’re vaping correctly.
Here are some vaping tips from the experts at Vaping 360 .
- Know your vaporizer and the kinds of oils and products it can accommodate.
- Start slowly and wait for the effects to kick in before you vape more.
- Make sure brands you buy have lab reports to confirm a lack of contaminants, including THC (if you’re trying to avoid that).
- Find an appropriate starting dose for your body weight.
Vaping 360 Recommends:
CBD Oil Vape
Read labels carefully to make sure the CBD oil you are interested in is suitable for vaping. Many CBD oils are designed for oral consumption and should never be used in vaporizing devices.
Consider if you really want to vape CBD oil or if you’re looking for CBD vape juice.
According to Vaping360 , many people casually say vaping “CBD oil” when they really mean “CBD vape juice.” These vaping experts recommend watching for the following keywords when looking for products that allow you to safely vaporize CBD oil:
- CBD oil vape pens
- CBD oil cartridges
- CBD oil pods
Don’t try to use CBD oil that was made for oral consumption in your vaporizer. This could damage your health and your vaporizing device.
CBD Oil Vape Pen Starter Kit
Discreet and sometimes disposable, vape pens provide an excellent way to try vaping CBD.
Vape pens: You can put them in your pocket, they don’t take up much room, and they usually require less upfront investment and knowledge that other forms of CBD, so they’re perfect for people who just want to try out vaping CBD.
Several companies have even designed starter kits to make your CBD vaping experiments as easy as possible.
You can choose from refillable pens and disposable pens.
- Disposable pens are ideal for people who think they may just want to experiment once.
- Refillable pens are best for people who know they might want to vape repeatedly.
CBD Vape Additive
CBD vape additives, often called e-liquids or e-juices on online stores, pair with CBD vape juices to enhance the flavors and effects of the vaping experience.
E-liquids and e-juices may or may not contain any of their own CBD.
These additives are best for experienced “vapers” who know how their devices work, what products work in their devices, and what they want to achieve.
This collection of vape additives has something for everyone. Here’s a shortlist of the selections:
Other CBD Products
Products labeled CBD isolates contain only the CBD from the cannabis plant. They do not contain other cannabinoids as full-spectrum CBD oils do.
According to Pure Kana , these are the key reasons someone might want to choose CBD isolate over full-spectrum CBD oil:
- CBD isolate is CBD in its purest form
- CBD isolate comes along with no risk of consuming THC, so it’s a good option for people with THC sensitivities or those worried about drug testing
- CBD isolate has no flavor, so it’s good for people who want to cook with CBD or just hate the taste of some CBD oils
CBD capsules provide an easy and fuss-free way to try CBD. They leave little chance of user error.
Some forms of CBD require users to measure out dosages or keep oils under their tongue for a satisfactory length of time. CBD capsules avoid all that. You just pop one in your mouth, and that’s it.
Many CBD capsules enter supplement territory as they might contain other beneficial botanicals or fatty acids.
For example, Charlotte’s Web makes a CBD capsule that includes phytocannabinoids, terpenes, flavonoids, and essential fatty acids.
CBD capsules are perfect for busy, on-the-go people who just want to get a little dose of CBD and then be on their way. They don’t want consuming CBD to be an “experience.”
- Charlotte’s Web CBD Capsules
- Veritas Farms CBD Capsules
CBD lotions and body products probably won’t give you a CBD buzz, but the compound’s anti-inflammatory properties and antioxidants might give you glowing skin.
We’ve already discussed CBD’s anti-inflammatory properties. These properties are the same reason CBD might benefit your skin in lotion form. You just apply a topical lotion to an inflamed area and observe the effects.
Some reports even suggest CBD could slow the production of oil, a compelling prospect if you have blemish-prone skin. While we are still learning more about the benefits of CBD to your skin, these positive reports show clear signs that it should be considered in your guide to healthy skin.
If lotions and beauty products interest you, then check out this CBD product roundup from the lifestyle aficionados at Allure.
CBD patches are designed to provide pain relief on a specific area of your body.
Some people seem to love their topical patches . The transdermal patches deliver CBD through the skin, so the effects should manifest quickly.
This might sound strange, but if heat patches and topical cooling creams relieve pain, then why not CBD patches?
- Trio Hemp Oil Topical Pain Patch (Hemp Only; no CBD)
- What reviewers say: Effective in relieving painful shoulder tension
- What reviewers say: Effective at managing pain
Hemp seeds make an effective way to grow hemp crops that will eventually produce CBD, but you have to really know how to plant the seeds.
Expert farmers in this Ag Professional article provide just a glimpse of how complicated growing hemp can be. Just some of the factors you would need to consider include:
- Planting seeds at the right depth
- Planting seeds at the right soil and surface area density
- Getting the timing right
The moral: Large-scale hemp farming is probably not accessible for people with no existing planting experience. Casual hemp growers can see this Morning Chores post on hemp growing to get an idea of how complicated growing hemp can be, even on a small scale.
A transdermal application of CBD simply means you absorb the compound through your skin.
Taking CBD through the skin might seem weird, but it actually has a variety of benefits as demonstrated by this study originally published in the European Journal of Pain .
Here’s a selection of noted benefits:
- Avoids degradation of CBD through metabolism (When you eat CBD, you have to metabolize it before it hits your bloodstream, and that process can reduce the potency.)
- Reduces inflammation in applied areas
- Reduces symptoms of pain
- Comes along with few observed side effects
Taken together, the main revelations of this study suggest transdermal CBD might help alleviate pain from arthritis and other conditions.
CBD sprays typically deliver low doses of CBD that are ideal for beginners.
Ideal for beginners and casual CBD users, CBD sprays deliver low doses through a mechanistic spray function that controls the amount of liquid you get with each spray. (Users don’t have to measure or pour anything.)
Reminiscent of Binaca breath freshening sprays, CBD sprays are fast and discreet. One quick pump is all you need, so you can get your CBD fix while keeping your habit on the down-low if that’s a concern to you.
CBD sprays come in flavored and unflavored versions to suit a variety of tastes. Plus, it’s easy to add to your dosage. Just count your sprays and continue until you achieve the effects you want.
CBD supplements may help you build on CBD’s effects to achieve other benefits.
CBD supplements, like this one from Plant People , usually combine CBD with other healthy natural ingredients to build on and maximize the benefits of CBD.
- This Stay Sharp supplement features herbal nootropics and adaptogens, and as the product’s name suggests, all the ingredients work together to help your brain achieve optimal function.
- Ingredients include bacopa monerri leaf extract and cordyceps extract.
- Ingredients include ashwagandha and Schisandra berry.
The capsules are also easy to transport, so you can take them with you everywhere.
CBD ointments make good options for people looking for pain relief in specific areas.
CBD ointments, like patches and other transdermal products, enter your body through the skin. They don’t risk the degradation or variation of CBD content that comes along with CBD edibles.
Ointments deliver CBD and its anti-inflammatory properties straight to the source of pain to achieve, with hope, fast and effective relief.
Tuck.com selected a roundup of their favorite CBD ointments and salves. Here are the brands featured:
Most CBD ointments will also contain other natural ingredients that provide even more benefits.
All in all, CBD ointments make a delightful and less invasive alternative to unhealthy pain killers.
CBD Massage Oil
The ultimate relaxing activity (message) meets the ultimate relaxing compound (CBD).
We all know massages can relax the mind and ease sore and tight muscles, so what happens when we add CBD to the mix?
The expert quoted in this Well + Good article explains why people might feel enhanced effects. CBD’s topical anti-inflammatory characteristics travel through the skin. When applied onto skin and muscles that have already been worked into relaxation by massage, CBD can turn up the volume on the benefits and sensations.
Also, since topical CBD affects only a single area, people probably won’t experience as much of the drowsiness, hunger, or sleepiness some feel when taking oral versions. (We wouldn’t want people falling asleep on their massage tables, after all.)
CBD Oil Drops
You can call any CBD oil that comes with a dropper “CBD oil drops.”
CBD oil drops aren’t like gumdrops or lemon drops or anything like that. CBD drops just label a method for delivering the dosage to your mouth, one dropper at a time.
Droppers make CBD oil dosage easy to measure, so you know how much you’re getting and how much works for you. Most products will list how much of one dropper you should take, full vs. half, etc.
Curious about CBD oil drops? Try PlusCBD™ Oil Drops , available in a variety of concentrations and flavors that go perfectly in smoothies and shakes and so much more.
CBD Oil Pills
CBD pills, often called CBD capsules, are easy to take and sometimes include other beneficial herbs and compounds.
- You get a controlled dosage without measuring and eyeballing. Simply swallow the capsule. You don’t have to worry about measuring into a dropper or following below-the-tongue instructions.
- They’re easy to transport.
- They’re fast to use.
- They’re discreet to pop at any time.
- They’re flavorless (ideal for people who gag when they take CBD oil)
CBD capsules look and feel a lot like any other multivitamin or supplement, so they’re comforting for people who feel strange about ingesting oils and tinctures.
- Modern Nature Relieved
We’d love to hear your thoughts about CBD Oil in the comments below… What has been your experience?